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Hailey 24 Fe Review

Hailey 24 Fe (ethinyl estradiol, norethisterone) is an oral hormonal contraceptive which is used for birth control in women.


Indications for use

  • Hormonal contraception;
  • Treatment of acne.

Mechanism of action

The active components of the medication, ethinyl estradiol and norethisterone, inhibit ovulation, cause changes in the cervical mucus, which makes it difficult for spermatozoa to enter the uterus.

Dosage and mode of application

Each pack of Hailey 24 Fe consists of 24 active tablets (each containing ethinyl estradiol and norethisterone) and 4 inert tablets (each containing ferrous fumarate). These last 4 tablets are used as “reminders”.

Take 1 tablet each day, for 28 days in a row, at about the same hour (preferable in the evening after meals). Intervals between tablets should not exceed 24 hours.

You can either take the first tablet on the Day 1 of your period (the day when menstruation begins) or on Sunday following the onset of your menstruation.

Once you’ve taken the last inert tablet from the blister, begin a new pack the next day. Use the same mode of intake for all next packs of Hailey 24 Fe.

Do not forget to take pills (especially those containing ethinyl estradiol and norethisterone) since missing pills reduces the reliability of the contraceptive drug.


There are no known cases of overdosage. Possible adverse reactions include nausea, vomiting, intermenstrual spotting/bleeding.

Side effects

The drug may cause the following adverse reactions:

  • breast tenderness;
  • brest pain;
  • pain;
  • pelvic fluid collection;
  • nipple pain;
  • nipple discharge;
  • bacterial vaginitis;
  • abnormal vaginal bleeding;
  • vaginal hemorrhage;
  • dysmenorrhea;
  • dysfunctional uterine bleeding;
  • thrombosis;
  • amenorrhea;
  • vaginitis;
  • breast secretion;
  • cervical secretion;
  • spotting;
  • cervical erosion changed;
  • premenstrual syndrome;
  • uterine fibroid disease exacerbated;
  • vaginal infection;
  • pollakiuria;
  • vaginal candidiasis;
  • painful menstruations;
  • dysuria;
  • pelvic pain;
  • ovarian cyst;
  • galactorrhea;
  • fibrocystic breast change;
  • breast disorder;
  • endometrial hyperplasia;
  • ovarian cyst;
  • uterine enlargement;
  • high blood pressure;
  • thrombosis;
  • menorrhagia;
  • metrorrhagia;
  • myocardial infarction;
  • hypertension;
  • palpitation;
  • tachycardia;
  • diabetes mellitus;
  • hypoglycemia;
  • abnormal blood glucose levels;
  • hypocalcemia;
  • angina pectoris;
  • hot flush;
  • irregular heart rate;
  • headache;
  • migraine,
  • dizziness;
  • cerebral hemorrhage;
  • cerebral thrombosis;
  • fainting;
  • hypoesthesia;
  • sensory disturbance;
  • transient ischemic attack;
  • ischemic stroke;
  • chorea;
  • hepatic adenoma;
  • hepatic carcinoma;
  • benign liver tumor,
  • breast cancer;
  • ovarian cancer;
  • endometrial cancer;
  • uterine cancer;
  • hypothyroidism;
  • nausea, vomiting;
  • abdominal pain;
  • bloating;
  • colitis;
  • dyspepsia;
  • inflammatory bowel disease;
  • Crohn’s disease;
  • ulcerative colitis;
  • constipation;
  • malaise;
  • chest pain;
  • pancreatitis;
  • liver disease;
  • gallbladder disease;
  • cholestatic jaundice, cholelithiasis;
  • mood swings;
  • depression;
  • anxiety;
  • insomnia;
  • panic attack;
  • reduced sex drive;
  • bipolar disorder;
  • irritability;
  • chloasma;
  • photosensitivity;
  • pruritus;
  • alopecia;
  • pulmonary embolism;
  • asthma;
  • dyspnea;
  • breakthrough bleeding;
  • breast enlargement;
  • anemia;
  • hypersensitivity;
  • contact lens intolerance;
  • cataracts;
  • retinal thrombosis;
  • disturbed vision;
  • fungal infection;
  • backache;
  • myalgia;
  • back pain;
  • impared renal function;
  • cystitis;
  • weight changes;
  • poor tolerance to carbohydrates;
  • changes in appetite;
  • increased triglycerides;
  • wedema;
  • fatigue, weakness;
  • porphyria;
  • acne;
  • loss of hair on the head;
  • aggravated epileptic seasures;
  • dementia;
  • melasma.


Do not use Hailey 24 Fe for birth control if you have any of the listed diseases/conditions:

  • pregnancy or breastfeeding period
  • diabetes (including in the anamnesis);
  • rash, hives, itching;
  • cardiovascular disorders such as blood clots, diseased blood vessels, heart disease (including in the anamnesis);
  • liver disease, liver tumor (including in the anamnesis);
  • severe headaches (including in the anamnesis);
  • hypertension (including in the anamnesis);
  • a history of heart attack, stroke, angina,
  • an abnormal cough, shortness of breath, swelling (including in the anamnesis);
  • endometrial cancer (including in the anamnesis);,
  • cancer of the cervix or vagina (including in the anamnesis);
  • vaginal bleeding of unknown origin (including in the anamnesis);
  • hypersensitivity to ethinyl estradiol/norethisterone or another component of the drug;
  • current use of ombitasvir, paritaprevir, ritonavir
  • you are planning to undergo a surgical intervention in 6 weeks
  • if have not started your periods
  • jaundice caused by the previous pregnancy or the previous use of other sex hormones.

If any of the mentioned conditions develop on the background of using birth control pill, stop taking them immediately and consult a doctor.


Do not use Hailey 24 Fe if you are currently taking dasabuvir, ritonavir, ombitasvir, or paritaprevir.

The contraceptive can also interact with:

  • acetaminophen;
  • rifapentine;
  • griseofulvin;
  • rifampin;
  • temazepam;
  • bosentan;
  • carbamazepine;
  • caffeine;
  • clofibrate;
  • pioglitazone;
  • mineral oil;
  • modafinil;
  • mycophenolate;
  • rifabutin;
  • penicillins;
  • phenytoin;
  • tamoxifen;
  • hydrocortisone;
  • nefazodone;
  • theophylline;
  • tetracyclines;
  • topiramate;
  • warfarin;
  • ascorbic acid;
  • prednisolone;
  • ritonavir or other drugs for HIV infection or AIDS;
  • rosuvastatin;
  • selegiline;
  • aprepitant;
  • thyroid hormones;
  • diazepam;
  • cyclosporine;
  • dantrolene;
  • felbamate;
  • grapefruit juice;
  • oxcarbazepine;
  • St. John’s Wort;
  • atorvastatin;
  • barbiturates.

Pregnancy and breastfeeding

Hailey 24 Fe is contraindicated during pregnancy and breastfeeding. You must ensure you are not pregnant prior to using this drug. Cancel hormonal contraception immediately if pregnancy occurs. The active substances of the drug may be excreted into breast milk.

What if I miss a pill?

If you miss 1 active pill in Weeks 1, 2 or 3:

Take the missed pill as soon as possible. Take the next pill at your usual time, keep taking 1 pill p3er day until you finish the pack. You do not need additional birth control methods.

If you miss 2 consecutive active pills in Week 1 or Week 2:

Take the 2 missed pills as soon as possible. Take the next 2 pills the next day. Keep taking 1 tablet each day until the pack is empty. You must you additional birth control methods (condoms or spermicides) if you have sex within 7 days after missing pills.

If you miss 2 consecutive active pills in Week 3 or Week 4 or you miss 3 or more active tablets in a row at any time:

  • Day 1 Start: Throw out the remaining pills and start a new pack immediately;
  • Sunday Start: Keep taking 1 pill per day until Sunday, then discard the rest of the pills and start a new pack immediately.

You must you additional birth control methods (condoms or spermicides) if you have sex within 7 days after missing pills.

If you miss any of the 4 inert pills:

Just throw them away. In this case, you do not need additional birth control methods.


Do not take the pills if you are pregnant or think you may be pregnant. Consult a doctor if you miss 2 menstrual periods in a row.

Taking combination oral contraceptives may increase the risk of blood clots, stroke, heart attack, especially if you have other risk factors, for example, excessive weight.

Smoking women have an increased risk of blood clots, stroke or heart attack. You should not take Hailey 24 Fe if you are a heavy smoker and are over the age of 35.

You are at risk if you have hypertension diabetes, high cholesterol, or excessive weight. The risk is especially high during your first year of hormonal contraception. The risk is also high when you resume taking the drug after a 4-weeks break.

The medication does protect you from sexually transmitted diseases, including HIV and AIDS.

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