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Jenest 28 Review

Jenest 28 (ethinyl estradiol and norethindrone) is an oral combined oral birth control pill used by women to prevent pregnancy.


Indications for use

Jenest-28 is used to prevent pregnancy.

It is used to treat endometriosis, heavy or irregular bleeding, abnormal absence of menses and pain during menses. It is also used as treatment for breast cancer.

Mechanism of action

This product contains 2 hormones: ethinyl estradiol and norethindrone. It works by inhibiting ovulation. It also has weak estrogenic and androgenic properties.

Dosage and mode of application

Use these pills as directed by your doctor. Study the label on the drug for exact dosing instructions.

  • Take 1 pill orally with water, with or without food;
  • Take pills at the same time every day, at intervals not exceeding 24 hours;
  • Do no skip doses;
  • Do not take 2 doses at once.

Side effects

In rare cases, the medicine can cause side effects, such as:

  • mild nausea;
  • stomach cramps;
  • headache;
  • breast pain;
  • vomiting;
  • bloating;
  • tenderness or swelling;
  • changes in weight or appetite;
  • vaginal itching or discharge;
  • changes in your menstrual periods;
  • decreased sex drive;
  • problems with contact lenses;
  • loss of scalp hair;
  • increased hair growth;
  • nervousness or dizziness;
  • freckles or darkening of facial skin.

Continue taking your pills, but discuss the adverse reactions with your doctor.


Do not take Jenest-28 if you have any of the following conditions (current of a history):

  • you are pregnant or have recently had a baby;
  • circulation problems;
  • abnormal vaginal bleeding;
  • hormone related cancer (breast or uterine);
  • stroke or blood clot;
  • jaundice caused by birth control pills;
  • liver disease or liver cancer.


Some medicines can make Jenest-18 less effective. The examples of such drugs are HIV or AIDS medications, seizure medications, Tylenol, prednisolone, theophylline, St. John’s Wort, vitamin C, antibiotics, barbiturate sedatives.

Pregnancy and breastfeeding

If you are pregnant or have recently had a baby, do not take these pills.

The hormones that are part of this drug can cause birth defects. If you have recently had a baby, you must wait 4 weeks before taking this product, or 6 weeks if you are breast-feeding.

What if I miss a pill?

If you miss an active pill of Jenest-28, take it as soon as you realize your mistake. If it is almost time for your next dose, skip the missed pill and follow your regular dosing schedule.


Birth control pill do not prevent the contraction of sexually transmitted diseases, such as HIV and AIDS. Only a condom can protect you from these diseases.

Smoking increases your risk of stroke, blood clots, heart attack and high blood pressure while on the pills. The risk of these adverse reactions increases with age and with the number of cigarettes you smoke per day. Do not smoke if you are taking oral contraceptives.

If you wear contact lenses, you may develop vision problems or your tolerance of the contact lenses may decrease.

Tell your doctor your entire medical history, most especially your hereditary predisposition to asthma, blood clots, kidney disease, liver disease, high blood pressure, stroke, heart disease.

An overdose of Jenest-28 can cause darkening of the skin on your face, and you should avoid prolonged sun exposure or sunlamps.

If you are planning surgery, tell your doctor or dentist you are taking hormonal contraceptives.

You may develop temporary infertility (several months) once you discontinue this product.

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