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Junel Fe 24 Review

Junel Fe 24 (ethinyl estradiol and norethisterone) is a hormonal birth control pill which is used for birth control in females.


Indications for use

  • Hormonal contraception.

Mechanism of action

The active components of Junel Fe 24, ethinyl estradiol and norethisterone, block ovulation, cause changes in the cervical mucus, which does not allow spermatozoa to penetrate the uterus.

Dosage and mode of application

Each pack Junel Fe 24 consists of 24 active pills (ethinyl estradiol + norethisterone) and 4 inert pills (ferrous fumarate). These last 4 pills serve as “reminders”.

You shoud take one pill per day, at about the same time of a day, for 28 days in a row.

You can either start the pack on the Day 1 of your menstrual bleeding or on Sunday following the onset of your period.

Once you’ve taken the last pill from the blister, begin a new pack without breaks. Follow the same mode of application for all subsequent cycles of the contraceptive.

Do not miss active pills since this may reduce the contraceptive effect of the drug.


There are no reports of overdosage. Possible consequences include nausea, intermenstrual spotting/bleeding, vomiting.

Side effects

In some cases, Junel Fe 24 may cause the following side effects:

  • abnormal vaginal bleeding;
  • vaginal hemorrhage;
  • dysmenorrhea;
  • dysfunctional uterine bleeding;
  • thrombosis;
  • amenorrhea;
  • vaginitis;
  • breast tenderness;
  • breast pain;
  • breast secretion;
  • cervical erosion changed;
  • premenstrual syndrome;
  • uterine fibroid disease exacerbated;
  • vaginal infection;
  • pollakiuria;
  • vaginal candidiasis;
  • painful menstruations;
  • dysuria;
  • angina pectoris;
  • hot flush;
  • pelvic pain;
  • ovarian cyst;
  • breast disorder;
  • nipple pain/discharge;
  • bacterial vaginitis;
  • endometrial hyperplasia;
  • ovarian cyst;
  • uterine enlargement;
  • high blood pressure;
  • thrombosis;
  • menorrhagia;
  • myocardial infarction;
  • hypertension;
  • diabetes mellitus;
  • cervical secretion;
  • spotting;
  • hypoglycemia;
  • abnormal blood glucose levels;
  • hypocalcemia;
  • irregular heart rate;
  • headache;
  • migraine,
  • dizziness;
  • cerebral hemorrhage;
  • cerebral thrombosis;
  • fainting;
  • transient ischemic attack;
  • ischemic stroke;
  • chorea;
  • galactorrhea;
  • fibrocystic breast change;
  • hepatic carcinoma;
  • benign liver tumor,
  • breast cancer;
  • ovarian cancer;
  • endometrial cancer;
  • uterine cancer;
  • hypothyroidism;
  • nausea;
  • vomiting;
  • dyspepsia;
  • inflammatory bowel disease;
  • Crohn’s disease;
  • ulcerative colitis;
  • constipation;
  • chest pain;
  • pancreatitis;
  • liver disease;
  • gallbladder disease;
  • asthma;
  • dyspnea;
  • cholestatic jaundice, cholelithiasis;
  • mood swings;
  • depression;
  • anxiety;
  • insomnia;
  • panic attack;
  • reduced libido;
  • photosensitivity;
  • pulmonary embolism;
  • porphyria;
  • acne;
  • breast enlargement;
  • anemia;
  • abdominal pain;
  • bloating;
  • colitis;
  • hypersensitivity;
  • discomfort when wearing contact lenses;
  • retinal thrombosis;
  • vision disorders;
  • backache;
  • myalgia;
  • back pain;
  • weight changes;
  • changes in appetite;
  • edema;
  • abnormal fatigue;
  • increased epileptic seizures;
  • loss of hair on the head;
  • bipolar disorder;
  • chloasma;
  • impaired renal function;
  • cystitis


Do not use Hailey 24 Fe for birth control if you have any of the listed diseases/conditions:

  • pregnancy;
  • breastfeeding period
  • diabetes (including a history);
  • rash, hives, itching;
  • treatment with ombitasvir, paritaprevir, or ritonavir;
  • age under 16;
  • cardiovascular disorders such as blood clots, heart disease (including a history);
  • vaginal bleeding of unknown etiology (including a history);
  • liver disease, liver tumor (including a history);
  • hypertension (including a history);
  • heart attack, stroke, angina (including a history);
  • severe headaches/migraines (including a history);
  • abnormal cough, shortness of breath (including a history);
  • endometrial cancer (including a history);
  • cancer of the cervix or vagina (including a history);
  • jaundice during the previous pregnancy or the previous use of sex hormones;
  • hypersensitivity to components of the drug.

If any of the listed diseases/conditions develops for the first time against the background of using the drug, cancel the hormonal contraception and visit a doctor.


It’s not recommended to use Hailey 24 Fe if you are taking any of the listed medications:

  • dasabuvir;
  • ritonavir;
  • ombitasvir;
  • mycophenolate;
  • rifabutin;
  • penicillins;
  • paritaprevir;
  • acetaminophen;
  • rifampin;
  • temazepam;
  • bosentan;
  • carbamazepine;
  • caffeine;
  • clofibrate;
  • warfarin;
  • ascorbic acid;
  • pioglitazone;
  • mineral oil;
  • modafinil;
  • phenytoin;
  • tamoxifen;
  • hydrocortisone;
  • nefazodone;
  • aloxifene;
  • theophylline;
  • tetracyclines;
  • rifapentine;
  • diazepam;
  • cyclosporine;
  • griseofulvin;
  • topiramate;
  • prednisolone;
  • ritonavir or other medications for HIV infection or AIDS;
  • rosuvastatin;
  • selegiline;
  • barbiturates;
  • aprepitant;
  • thyroid hormones;
  • felbamate;
  • grapefruit juice;
  • oxcarbazepine;
  • St. John’s Wort;
  • dantrolene;
  • doxercalciferol;
  • atorvastatin.

Pregnancy and breastfeeding

Junel Fe 24 is NOT indicated for use during pregnancy and breastfeeding (lactation) period. Discontinue taking the pills if pregnancy occurs. The active components of the drug (ethinyl estradiol and norethisterone) may get into breast milk.

What if I miss a pill?

You missed 1 pill in Weeks 1, 2 or 3:

The missed pill is taken as soon as you remember. The next pills are taken at your regular time until the pack is finished. In this case, you do not need backup methods of contraception.

You missed 2 pills in a row in Week 1 or 2:

The 2 missed pills are taken as soon as you remember. The next 2 pills are taken the next day. Then take 1 pill per day until you finish the pack. In addition, you must use backup methods of contraception for 7 days after missing pills.

You missed 2 pills in a row in Week 3 or 4 or you missed 3 or more active pills in a row at any time:

  • Day 1 Start: Discard the remaining pills and begin a new pack the same day;
  • Sunday Start: Taking 1 pill each day until Sunday, then throw out the remaining pills and begin a new pack the same day.

In any case, you must use backup methods of contraception for 7 days after missing pills.

You missed any of the 4 reminder pills:

Discard the missed pills, keep taking 1 pill each day until the pack is finished. In this case, you do not need backup methods of contraception.


Junel Fe 24 will not protect you from sexually transmitted diseases.

Do not use hormonal contraceptives if you are pregnant or suspect your pregnancy. Consult your doctor immediately if you become pregnant or if you have no menstrual cycles 2 times in a row.

After delivery, you should wait 4 weeks before taking the drug.

Taking this drug may increase the risk of blood clots, heart attack, or stroke, especially if a patient has other risk factors.

Take the medication with extreme caution if you have hypertension, diabetes, overweight, or high cholesterol levels. The risk is especially high during your first year of using birth control pills.

Smoking patients have an increased risk of stroke, heart attack, or blood clots. Do not use Junel Fe 24 for birth control if you are smoking and are over 35 years of age.

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