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Larin 1/20 Review


Larin 1/20 is a combination birth control pill which is used to prevent unwanted pregnancy. The drug contains 2 hormones, ethinyl estradiol and norethisterone.

Contents:

Indications for use

  • Hormonal contraception.

Mechanism of action

The drug prevents the full development of a woman’s egg each month. The egg can no longer accept a sperm and fertilization is prevented.

Dosage and mode of application

Larin 1/20 pack consists of 21 pale yellow tablets. Each tablet contains norethindrone acetate 1 mg and ethinyl estradiol 20mcg.

Take your first pill on the first day of your menstrual bleeding or on the first Sunday after your menstruation begins. You may need to use an additional method of contraception (condoms or spermicides) when you first start taking birth control pills. Follow your doctor’s instructions.

Take 1 pill per day, for 21 days in a row. Intervales between doses should not exceed 24 hours. Once you have taken the last pill from the blister, make a 7-day break, then start a new pack. Menstrual bleeding should occur 2-3 days after you have taken the last pill from the blister. Do not miss pills because in this case, you may g

Do not take excessive doses of this drug.

Overdose

Overdose can cause nausea, passing out, trouble breathing, vaginal bleeding, vomiting. If you have taken an excessive dose of ethinyl estradiol and norethisterone, contact your doctor.

Side effects

Many people using Larin 1/20 do not have serious side effects. In rare cases, the drug can cause:

  • high blood pressure;
  • lumps in the breast;
  • mental/mood changes (depression);
  • severe stomach/abdominal pain;
  • unusual changes in vaginal bleeding (continuous spotting, sudden heavy bleeding, missed periods);
  • dark urine;
  • yellowing eyes/skin;
  • blood clots (deep vein thrombosis, heart attack, pulmonary embolism, stroke);
  • chest/jaw/left arm pain;
  • confusion;
  • sudden dizziness/fainting;
  • pain in the groin/calf;
  • slurred speech;
  • sudden shortness of breath;
  • rapid breathing, unusual headaches;
  • vision changes;
  • lack of coordination;
  • worsening of migraines;
  • very severe headaches;
  • unusual sweating;
  • weakness on one side of the body;
  • vision problems/changes (partial/complete blindness);
  • allergic reaction (rash, itching, swelling of the face/tongue/throat);
  • severe dizziness;
  • trouble breathing.

If you notice any unusual health problems after taking the contraceptive, contact your doctor.

Contraindications

Larin 1/20 tablets should not be used in the presence of the conditions listed below:

  • established or suspected pregnancy;
  • thrombophlebitis or thromboembolic disorders;
  • hepatic adenomas or carcinomas;
  • deep vein thrombophlebitis or thromboembolic disorders in the anamnesis;
  • established or suspected breast cancer;
  • cancer of the endometrium or other estrogen-dependent neoplasia;
  • abnormal genital bleeding;
  • cerebral vascular or coronary artery disease;
  • cholestatic jaundice of pregnancy or jaundice with prior pill use;
  • treatment with hepatitis C drugs, such as ombitasvir/paritaprevir/ritonavir, with or without dasabuvir.

Interactions

Larin 1/20 may interact with the following products:

  • aromatase inhibitors (anastrozole, exemestane);
  • ospemifene;
  • tamoxifen;
  • tizanidine;
  • tranexamic acid;
  • drugs used to treat chronic hepatitis C (ombitasvir/paritaprevir/ritonavir with or without dasabuvir);
  • rifamycins (rifampin, rifabutin);
  • St. John’s wort;
  • drugs used to treat seizures (barbiturates, carbamazepine, felbamate, phenytoin, primidone, topiramate);
  • HIV drugs (nelfinavir, nevirapine, ritonavir);
  • griseofulvin;
  • modafinil.

Before using hormonal contraceptives, tell your doctor if you are currently taking any other drugs and discuss if you should use an additional method of contraception.

This drug may affect certain laboratory tests (blood clotting factors, thyroid), causing inaccurate results. Make sure your doctor knows you use this contraceptive.

Pregnancy and breastfeeding

The drug is contraindicated for use during pregnancy. Discontinue hormonal contraception if pregnancy occurs. Do not use this contraceptive if you are breast-feeding a baby. The active substances can enter breast milk and affect the baby. Besides, this medicine may slow the production of breast milk.

What if I miss a pill?

Missing a pill of Larin 1/20 increases your risk of becoming pregnant, so try not to miss doses.

  • If you miss 1 pill, take 2 pills on the day you remember. Then take 1 pill each day until you finish the pack;
  • If you miss 2 pills in a row in Week 1 or 2, take 2 pills a day for 2 days in a row. Then take 1 pill each day until the pack is empty. Use a barrier method of contraception for 7 days following the missed pills;
  • If you miss 2 pills in a row in Week 3, discard the rest of the pills and start a new pack the same day if you are a Day 1 starter. If you are a Sunday starter, take 1 pill each day until Sunday. On Sunday, discard the remaining pills and start a new pack that same day;
  • If you miss 3 pills in a row in Week 1, 2, or 3, discard the rest of the pills and start a new pack that same day if you are a Day 1 starter. If you are a Sunday starter, take 1 pill each day until Sunday. On Sunday, discard the remaining pills and start a new pack that same day.

If you forget to take 2 or more pills, you may miss a period during this month. If you have no menstrual bleeding for 2 months in a row, contact your doctor as soon as possible because you might be pregnant.

Precautions

Some patients may have spotting, especially during the first 3 months. Consult your doctor if bleeding continues or is unusually heavy.

Use an additional, non-hormonal method of birth control if you have severe vomiting or diarrhea.

If you are planning a serious surgery or prolonged bed rest, you should stop using this drug for a while. Your doctor or surgeon should know that you are taking birth control pills.

While using Larin 1/20, you will need to undergo medical examinations every 6 months.

If you are smoking, you have an increased risk of cardiovascular problems with severe consequences. Do not use this contraceptive if you are smoking and are over 35 years of age.

Tell your doctor if you have ever had heart problems, severe migraine, diabetes, hypertension, gallbladder disease, irregular periods, lumps, nodules, underactive thyroid, liver or kidney disease, fibrocystic breast disease, high cholesterol or triglycerides, overweight, depression, an abnormal mammogram.

The medicine will not protect you from HIV, AIDS, or other sexually transmitted diseases.

If you have recently had a baby, you will need to wait 4 weeks prior to using this drug.

Store the drug at room temperature away from moisture, heat, and kids.

Discard the unused pills after the expiration date.

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