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Estrostep Fe Review

Estrostep Fe is a birth control drug. It is triphasic hormonal contraceptive means prescribed to prevent an unwanted pregnancy.


Indications for use

Estrostep Fe is prescribed for birth control. The additional application lies in dysmenorrhea, sterility, uterine hypoplasia.

Mechanism of action

It is a contraceptive means. This birth control drug is a combined low dose containing estrogen and progestin. It suppresses the pituitary secretion of gonadotropic hormones. The contraceptive effect is achieved by means of the blocking effect of the gestagen and estrogenic constituents on the hypothalamic-pituitary-ovarian system. The estrogen constituent is a highly effective oral medication where ethinyl estradiol is a synthetic analog of the follicular hormone estradiol, which participates with the hormone of the Ferrum ferrate. The progestogenic component of the drug is norethisterone, which suppresses the synthesis of LH and FSH. It blocks an ovulation. Due to the combination of estrogen with progestin, Estrostep Fe with appropriate regimens can both stimulate and delay menstruation and help stop the acyclic uterine bleeding.

Mode of application and dosage

Estrostep Fe is prescribed as a 28-days course. The triphasic medication contains various hormone dosage and the latest 7 placebo pills. The pill is taken on a daily basis without any breaks. The pill should be washed down with a glass of water. When you apply the latest 7 pills known as placebo the menstruation will come.


There are the following contraindications when you take Estrostep Fe:

  • hypersensitivity;
  • thrombosis (venous and arterial) and thromboembolism;
  • conditions foregoing thrombosis inclusively of angina pectoris;
  • cerebrovascular dysfunctions (stroke, transient ischemic attacks);
  • multiple or expressed risk factors of venous or arterial thrombosis;
  • diagnosed or suggested migraine accompanied focal neurological symptoms;
  • diabetes manifested itself by vascular complications;
  • diagnosed or suggested pancreatitis with severe hypertriglyceridemia;
  • severe liver failure or liver disorders, including Dubin-Johnson and Rotor’s syndromes;
  • benign or malignant hepatic tumors;
  • specified hormone-dependent malignant neoplasms;
  • the age under 18 years;
  • vaginal hemorrhages of unclear etiology;
  • obesity (body mass index more than 30 kg/m2);
  • major trauma;
  • pregnancy;
  • lactation.

Side Effects

  • Nausea, vomiting, epigastric pain;
  • Spotting (bleeding);
  • Breast tenderness;
  • Mood changes (tearfulness, depression, irritability);
  • Slight hair loss;
  • Headache;
  • Acne (pimples), oily skin;
  • Pain in the legs’ muscles;
  • Amenorrhea (absence of menstruation);
  • Weight gain.


  • There is an increase in the metabolism of steroid hormones when taking barbiturates, antiepileptic drugs (carbamazepine, phenytoin).
  • Antibiotics (ampicillin, rifampicin), changing the intestinal microflora, reduce the effective concentration.
  • Means for general anesthesia, narcotic analgesics, anxiolytics, antiepileptic drugs, some antihypertensive drugs, ethanol reduces the contraceptive effectiveness.
  • If you take hypoglycemic drugs together with birth control pills the dosage correction may be required.

What if I miss a dose?

If you are late in taking the pill for less than 12 hours, contraceptive protection is not destroyed. The pill must be taken immediately, as soon as the woman understands the missed pill, the next pill should be taken at the usual time.

If you are late in taking the pill for more than 12 hours, contraceptive protection can be decreased considerably. In this case, you must follow the basic rules and take relevant measures given on the blister or by your doctor.

Estrostep Fe and pregnancy

Estrostep Fe is contraindicated during pregnancy. The application of this drug may bring the damage to an unborn child. This drug is also contraindicated during breastfeeding because it may penetrate the breast milk and bring damage to a child’s health.

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