Femcon Fe is a monophasic drug prescribed for an oral contraception. The main components are norethindrone and ethinyl estradiol plus Ferrum ferrate.
Indications for use
Mechanism of action
Femcon Fe is a low dose monophasic oral combined estrogen-gestagen contraceptive drug.
The contraceptive effect is carried out by means of complementary mechanisms, the most significant of which is comprised of an ovulation inhibition and the changes in the cervical secretion properties.
In addition to contraceptive action, combined oral contraceptives have other positive effects. The menstruation becomes more regular, less painful, the intensity of bleeding is reduced, preventing the risk of iron deficiency anemia. In addition, there are data on the reduction in the risk of endometrial and ovarian cancer.
Mode of application and dosage
Femcon Fe package contains 28 pills. 21 includes in its structure active hormones when other 7 pills are comprised of Ferrum ferrate. The drug should be taken at one and the same time within 28 pills. The pill is washed down with a full glass of water. During the application of the latest 7 inactive pills, the menstruation will start. There are no interruptions between the drug application.
Femcon Fe should not be used in the presence of any of the conditions listed below which are proved to be a direct contraindication:
- thrombosis (venous and arterial) and thromboembolism diagnosed or prior transferred (including deep vein thrombosis, pulmonary embolism, myocardial infarction, cerebrovascular disorders, for example, stroke;
- conditions preceding thrombosis (including transient ischemic attacks, angina pectoris) diagnosed or prior transferred;
- multiple or pronounced risk factors for venous or arterial thrombosis;
- pancreatitis with severe hypertriglyceridemia diagnosed or prior transferred;
- migraine with focal neurologic symptoms diagnosed or prior transferred;
- diabetes mellitus with vascular complications;
- hepatic failure and severe hepatic disease;
- hepatic tumors (benign or malignant) diagnosed or prior transferred;
- diagnosed hormone-dependent malignant diseases (including genital organs or mammary glands);
- vaginal bleeding of unknown etiology;
- hypersensitivity to any of the drug components.
The use of Femcon Fe can be accompanied by:
- the appearance of chloasma;
- change in libido;
- change in body weight;
- fluid retention;
- decreased mood;
- engorgement of mammary glands;
- breast pain;
- skin rash;
- secretions from the nipples;
- intolerance to contact lenses;
- change in vaginal secretion;
Interaction with certain drugs can result in breakthrough bleeding and/or a reduction in the contraceptive effect. During the reception of such drugs, a woman should additionally use the barrier method of contraception or choose another method of contraception.
- During the administration of drugs that affect microsomal enzymes, and within 28 days after their withdrawal, the barrier method of contraception should be used additionally.
- During the reception of antibiotics (with the exception of rifampicin and griseofulvin) and within 7 days after their withdrawal, the barrier method of contraception should be used additionally. If the period of use of the barrier method of preventing unwanted pregnancies ends later than the tablets in the package, you need to start a new package of Femcon Fe.
- Drugs that reduce contraceptive effect include drugs that induce hepatic enzymes (increase liver metabolism): phenytoin, barbiturates, primidone. carbamazepine and rifampicin; There are also suggestions for oxcarbazepine, topiramate, felbamate, ritonavir and griseofulvin, and preparations containing St. John’s Wort.
- HIV proteases (eg, ritonavir) and non-nucleoside reverse transcriptase inhibitors (such as nevirapine), and their combinations, can potentially influence hepatic metabolism.
- Contraceptive protection decreases with the intake of antibiotics (such as penicillins and tetracyclines), because, according to some data, they can reduce the intrahepatic circulation of estrogens, thereby lowering the concentration of ethinyl estradiol.
- This birth control drug can affect the metabolism of other drugs, which leads to an increase (for example, cyclosporine) or a decrease (for example, lamotrigine) of their concentration in blood plasma and tissues.
What if I miss a dose?
If the delay in taking the next tablet is less than 12 hours, the contraceptive effect remains. Take the pill as soon as you remind. Take the next tablet at the usual time. If the delay in taking the tablet is more than 12 hours, the contraceptive protection may be reduced.
In this case, you can follow 2 basic rules:
- the drug application should, in no case, be interrupted for more than 7 days;
- 7 days of continuous intake of tablets are required to achieve adequate suppression of hypothalamic-pituitary-ovarian regulation.
Femcon Fe and pregnancy
Femcon Fe is a drug not intended for the application during pregnancy and lactation.