Vienva is a microdose monophasic birth control medication. The drug is intended for pregnancy prevention.
Indications for use
Mechanism of action
Vienva is a microdose monophasic oral combined (estrogen + gestagen) contraceptive. Under the influence of levonorgestrel, the blockade of releasing factors (luteinizing and follicle-stimulating hormones and follicle-stimulating hormones) of the hypothalamus appears, inhibiting the secretion of the gonadotrophic hormones by the pituitary gland. Such a suppression leads to inhibition of maturation and release of the ovum for fertilization. There are changes in the endometrium, preventing the implantation of a fertilized egg. Ethinyl estradiol magnifies the viscosity of the cervical secretion, resulting in an obstacle for spermatozoa to enter the uterine cavity.
Mode of application and dosage
Vienva pills should be applied in the order specified on the blister daily at about the same time. The package contains 28 tablets. Apply 1 tablet daily for 28 days without interruptions. Tablets from each subsequent package should be taken after an application of 7 inert pills, during which the menstruation usually starts.
The menstruation usually starts on the 2nd or 3rd day after the last pill is applied, and it can continue until the taking of the tablets from the next package containing hormones.
Tablets should be taken on the first day of menstruation. It is possible to start the regimen from the 2nd-5th day of menstruation, but in this case, simultaneous use of additional barrier methods of contraception is recommended during the first 7 days.
The following contraindications may occur when taking Vienva:
- hypersensibility to the drug components;
- liver disease of severe form;
- congenital hyperbilirubinemia;
- presence or indication in the anamnesis of severe cardiovascular and cerebrovascular disorders;
- thromboembolism including of predisposition to it;
- hepatic tumors;
- malignant tumors;
- primarily breast cancer or endometrial cancer;
- hyperlipidemia in close relatives;
- arterial hypertension of severe forms;
- diabetes and other diseases of the endocrine glands of severe forms;
- sickle-cell anemia;
- chronic hemolytic anemia;
- hydatid mole;
- age over 40 years;
- vaginal bleeding of unclear genesis;
- idiopathic jaundice of pregnant women in the medical history;
- severe itching of pregnant women;
- herpes pregnant.
This birth control drug is taken with caution in the following cases:
- diseases of the liver and gallbladder;
- ulcerative colitis;
- uterine myoma;
- renal disease;
- adolescence age without regular ovulatory cycles.
The incidence of adverse reactions listed below was determined according to the following (World Health Organization classification):
- very often – more than 1/10;
- often from more than 1/100 to less than 1/10;
- infrequently – from more than 1/1000 to less than 1/100;
- rarely from more than 1/10000 to less than 1/1000;
- very rarely – from less than 1/10000, including individual occasions.
- often – nausea, gastralgia, darkening the teeth enamel;
- infrequently – vomiting, constipation, diarrhea;
- rarely – cholestasis;
- very rarely – pancreatitis, jaundice, hepatocellular adenoma.
- often – a feeling of tension, tenderness of the mammary glands;
- rarely – changes in libido, increase and secretion of the mammary glands;
- metrorrhagia during the first few months of admission, changes in vaginal secretion.
- often – headache, anxiety, depression;
- infrequently – a migraine.
very rarely – thrombophlebitis, thromboembolism.
Organs of sense:
very rarely – visual impairment, hearing loss.
- infrequently – fluid body retention, hyperlipidemia;
- rarely – allergic reactions (skin rash, itching, eyelid edema, conjunctivitis), poor tolerance of contact lenses, change in body weight;
- very rarely – a violation of the exchange of Na + and Ca2 +;
- in the case of the long-lasting use – chloasma (focal pigmentation).
The possible improvement of the steroid hormones is got in the case of the simultaneous application with barbiturates, some antiepileptic medications (carbamazepine, phenytoin).
Effective concentration decrease may be found with the simultaneous use of certain antibiotics (ampicillin, rifampicin, tetracycline, griseofulvin) due to changes in intestinal microflora. Nonsteroidal anti-inflammatory drugs (NSAIDs) decrease the effectiveness of this birth control drug.
You may need to adjust the dosage regimen in the case of a simultaneous application with hypoglycemic drugs.
What if I miss a dose?
The skipped pill of Vienva should be taken within the next 12 hours. If 36 hours have passed since taking the last pill, contraception cannot be considered reliable. In such cases, in order to prevent possible intermenstrual bleeding, the drug should be taken from the package already started.
In case of missing the timely taking of tablets, it is recommended to apply the additional non-hormonal method of contraception (for example, barrier).
Vienva and pregnancy
Contraindicated use during pregnancy or suspected of it and lactation (breastfeeding).