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Larissia Review

Larissia is a hormonal birth control drug. The contraception is provided by a suppression of ovulation. Moreover, the cervical secretion increase contributes to the impossibility for spermatozoa to penetrate into the uterine cavity.


Indications for use

Oral contraception is carried out by means of Larissia, a birth control drug containing ethinyl estradiol and levonorgestrel.

Mechanism of action

Various factors contribute to providing a contraceptive effect. The most significant are proved to be a suppression of ovulation and a change in the cervical mucus viscosity.

Additionally to birth control уааусе, combined oral contraceptives have some зерук benefit effects. The periods become more regular and less painful. One more effect lies in the intensity of the decrease in bleeding. As a result, the rate of iron deficiency anemia diagnosis is reduced.

Mode of application and dosage

Larissia should be taken on a daily basis independently on the meal. The same time regimen should be followed. The tablets are taken as a long-lasting regimen. One tablet per day should be taken in a raw for 28 days. Menstruation usually starts during the reception of the placebo pills.


Larissia should not be used in the presence of the following health conditions:

  • hypersensitivity to any of the drug’s components;
  • presence of thromboses (venous and arterial) presently diagnosed or in the medical history (eg deep vein thrombosis, pulmonary embolism, myocardial infarction, cerebrovascular disorders);
  • conditions preceding thrombosis (eg, transient ischemic attacks, angina pectoris);
  • diabetes mellitus or some diabetic disorders;
  • severe or multiple risk factors for venous or arterial thrombosis;
  • severe forms of liver disease;
  • liver tumors (benign or malignant);
  • diagnosed or suspected hormone-dependent malignant diseases (eg genitals or mammary glands);
  • vaginal bleeding of unclear etiology;
  • pregnancy.

Side effects

The following side effects of Larissia were described in women applying this birth control drug, but their relationship with the drug was neither confirmed nor disproved:

  • hypersensitivity;
  • tenderness and tension of the mammary glands;
  • enlargement of the mammary glands;
  • secretion from the mammary glands;
  • headache;
  • migraine;
  • change in libido;
  • mood decrease/change;
  • poor tolerance of contact lenses;
  • nausea;
  • vomiting;
  • other gastrointestinal disorders;
  • changes in vaginal secretion;
  • various skin disorders;
  • fluid retention;
  • change in body weight.

Sometimes chloasma can develop, especially in women with a history of chloasma during pregnancy.


Drug interactions, as a result of which the clearance of sex hormones is magnified, can lead to breakthrough bleeding and/or a decrease in birth control capacity.

This aspect was defined when a person takes phenytoin, barbiturates, primidon, carbamazepine and rifampicin. This list may be replenished by oxcarbazepine, topiramate, felbamate and griseofulvin. The mechanism of this interaction is based on a change in the functioning of hepatic enzymes.

Contraceptive protection is decreased by taking antibiotics (such as ampicillin and tetracyclines). The mechanism of this action is not examined properly.

Women taking any of the above medications as a short course, additionally to Larissia, should temporarily utilize the barrier method of contraception during concomitant use of the drugs and within 7 days after their withdrawal. During the reception of rifampicin and within 28 days after it is discontinuation, a barrier method should be applied, as well.

Women who take these drugs as a long-term course should apply other (non-hormonal) methods of contraception (eg a condom).

What if I miss a dose?

There are 2 timeframes of skipped birth control pills. They are:

  • less than 12 hours;
  • more than 12 hours.

In the first case, a woman should take the pill after the moment of the understanding. The contraceptive effect is maintained. In the second case, a woman should take the pill immediately. The contraceptive effect is reduced that’s why to protect yourself it is necessary to apply additional contraception methods.

Larissia and pregnancy

This drug is contraindicated during pregnancy and breastfeeding.

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