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Azurette Review


Azurette is a birth control medication. It contains ethinyl estradiol and desogestrel preventing ovulation. The egg maturation is also impossible.

Contents:

 

Indications for use

  • Premenstrual syndrome;
  • Functional disorders of the menstrual cycle;
  • Oral contraception.

 

Mechanism of action

Desogestrel – after ingestion is well and quickly absorbed in the digestive tract. Bioavailability is 62-81% (it is metabolized in the intestinal wall and by the liver). The combination with proteins is 98%. It is excreted in urine and feces in the form of metabolites.

Ethinyl estradiol – after oral administration quickly and almost completely absorbed from the digestive tract. Bioavailability is 60% (it is metabolized by absorption and by the liver). The connection with proteins is 98%. It is excreted in the urine and bile in the form of metabolites.

Mode of application and dosage

It is intended for an oral administration. Azurette dosage regimen includes the same time of the day application to prevent pregnancy from 1-5 day of menstruation. The formula looks like 1 tablet per day for 21 days, then 7-days break. The 8th day sees the start of a new pacage application.

Contraindications

It may cause a delay in sodium and water ions in the body.

Other contraindications are:

  • cardiovascular diseases;
  • kidney function disorders;
  • hypertension;
  • epilepsy;
  • bronchial asthma.

VT (intraocular pressure) may increase in case of closed-angle glaucoma. In connection with the emergence of breakthrough bleeding, it should be appointed cyclically. Discontinue if the following side effects occur:

  • migraine and headache;
  • acute visual impairment;
  • signs of thrombophlebitis or thromboembolism;
  • increased blood pressure (arterial pressure);
  • jaundice (cholestatic);
  • prolonged immobilization.

Taken with caution in the treatment of patients suffering from epilepsy, migraine, asthma, frequent depressions, impaired liver or kidney function. It may cause an exacerbation of the symptoms of porphyria and endometriosis.

There is an increased risk of endometrial cancer in postmenopausal women receiving uncompensated (without progestin) estrogen therapy for a long time. Men who receive therapy should regularly examine the mammary glands.

Information for a Patient:

  • Possibility of dizziness;
  • be careful when driving vehicles and working with operational machines.

Realize the risk of developing thrombophlebitis, retinal or cerebral thrombosis. If there are suspicions or confirmed such violations, stop taking Azurette.

Side effects

  • Headache;
  • Gastralgia;
  • Nausea;
  • Vomiting;
  • Mammary glands tenderness;
  • Weight gain;
  • Violation of glucose tolerance;
  • Fluid retention in the body;
  • Change in libido;
  • Decreased mood;
  • Edema of the eyelids;
  • Skin rash;
  • Erythema nodosum;
  • Conjunctivitis;
  • Unpleasant sensations when wearing contact lenses;
  • Impaired perception (visual impairment, hearing loss, flickering before the eyes);
  • Thrombophlebitis;
  • Thromboembolism;
  • Generalized itching;
  • Cholelithiasis;
  • Increased blood pressure;
  • Intermenstrual bleeding;
  • Changes in vaginal secretion (possible development of vaginal candidiasis).

 

Interactions

  • The possible reduction of the contraceptive effect: hepatic enzymes such as rifampicin, phenobarbital derivatives, anticonvulsants (phenytoin, carbamazepine), dihydroergotamine, certain tranquilizers, phenylbutazone, ketonazole, as well as broad-spectrum antibiotics (tetracycline, chloramphenicol, ampicillin, neomycin) with inductors. it is possible to (these combinations are not recommended).
  • The dose agjustment: indirect anticoagulants, an anticoagulant action
  • With simultaneous use with tricyclic antidepressants, maprotiline, BAB, an increase in bioavailability and, in connection with this, the toxicity of these drugs is possible.
  • With simultaneous use with oral hypoglycemic drugs or insulin, it is possible to disrupt the control of the state of carbohydrate metabolism (if necessary, correct the dosage regimen).
  • With the simultaneous use of regulon with bromocriptine, a possible decrease in efficiency is possible.
  • When used simultaneously with hepatotoxic drugs, especially with dantrolene, the risk of hepatotoxic action is significantly increased, especially in women over 35 years of age.

 

What if I miss a dose?

If the woman skips the pill or forget to take it on time, and if no more than 12 hours pass, you just need to take a forgotten pill, and then continue the reception at the usual time. If more than 12 hours have passed between taking the tablets, the contraceptive effect is not guaranteed, and additional methods of contraception are recommended.

If you miss 1 tablet on the first or second week of the cycle, you need to take 2 tablets the next day and then continue the regular application supplied by additional contraceptive methods until the end of the menstrual cycle.

If you miss a pill on the 3rd week of the cycle, you must take a forgotten pill, continue with regular intake and do not take a 7-day break. It is important to remember that in connection with the minimal dose of estrogen, the risk of ovulation and/or bleeding is increased when a pill is missed. Hence, the additional methods of contraception are recommended.

What should I do if I vomit or have diarrhea?

If vomiting or diarrhea occurs after taking the drug, then the drug absorption may be inadequate. If the symptoms have stopped within 12 hours, then you need to take another pill in addition. After this, you should continue taking the tablets in the usual way. If symptoms continue for more than 12 hours, then additional methods of contraception should be used during vomiting or diarrhea and for the next 7 days.

Azurette and pregnancy

The drug use during pregnancy and during breastfeeding is contraindicated. During the period of breastfeeding, it is necessary to decide whether to abolish the drug or stop breastfeeding.

Reviews

★★☆☆☆
After a year of taking Azurette, migraines with aura appeared. At first, I did not know what it was and why it appears. The gynecologist told me to withdraw the drug. Naturally, as soon as I finished the pack I threw it away. In the first 2 weeks, everything was fine. Then, incomprehensible pains began in the right ovary a week later. Periods in the first month came almost on time. Everything was good and tolerant. Then acne came in manyfold greater. Now, I definitely do not recommend it. While you take it, everything is great. I lived for a year and a half with a clean face, painless periods and everything was fine. But now I am suffering after the discontinuation.
- Rebecca

★★★★☆
I decided to take this drug 3 months ago. At the right moment, I continue to take it, but in the future, I plan to withdraw since this is a potent drug. I’ll start taking this drug, not for medical reasons, but with the goal of diversifying an intimate life with a regular partner. Almost immediately after the start, I experienced a strange adverse reaction, my legs started to hurt like hell for about a month. I have clean skin, but acne appeared in my first month. In the second month of application, this adaptation acne disappeared, the legs stopped hurting, the mood stabilized. In general, I can recommend this drug, just consult your doctor towardly.
- Faith

★★★☆☆
Acne tormented all my conscious life. For a long time, it was decided to take COCs and now I really regret it. I took them 2 times for 5 months, there was a 3-months break between doses, after which my life turned into continuous stress. I decided to withdraw it. But, unfortunately, the withdrawal process is too hard, I can't help discontinuing it. In general, since there were no special improvements for the second time, I decided to try again to quit Azurette. It is very strange that the first and second tricks gave such a different result. There is only the first month of cancellation, but the hair has already begun to fall out more severe. The swelling has appeared. I try to control myself, I take vitamins. Believe they will help me improve health conditions.
- Katherine

★★☆☆☆
I have never been for Azurette. But, alas, an unpleasant female disease appeared due to an unbalanced hormone level caused by stress. I underwent a bunch of tests. My gynecologist told me to take Azurette for 4 months. I was depressed, but I was convinced that I should take these tablets if I do not want to accomplish with the operation and/or infertility. I have been taking them for the second month. All month I had periods! At first, there was menstruation, then one day - off, then for more than 3 weeks, there were periods, then one day - off - and menstruation again. I can't enjoy sexual life, nor to engage in the sports activity. I can’t say that the drug is guilty. I hope the drug is still effective for most women.
- Kiera

★★★★☆
Everything went well with Azurette. These pills are easy to use. But still, Azurette had to be canceled on the 5th pack because periods' failures started. My mood began not only to swing but to deteriorate so much that it became a problem for me and my loved ones. I cannot say unequivocally that this drug is ineffective. It didn’t suit me but a doctor’s consultation will help you find out whether it is suitable for you.
- Brooke

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