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Cesia Review

Cesia is triphasic birth control pill which contains a combination of hormones, ethinyl estradiol and desogestrel, that are used to prevent ovulation.


Indications for use

Cesia contraceptive is indicated for use by women and girls of childbearing age to prevent unwanted pregnancy, reduce the symptoms of premenstrual syndrome, smooth the hormonal background and resume regular cycles in various systemic endocrine pathologies. The medication is also prescribed for the treatment of functional ovarian cysts, for the treatment of secondary infertility, cervical cancer.

When you take Cesia to prevent pregnancy, remember that this method of contraception does not protect against diseases that are sexually transmitted (HIV infection, hepatitis, chlamydia, etc.). In the absence of a regular sexual partner or if your partner has bacterial and viral venereal diseases, it is strongly recommended to use barrier contraceptive methods (condoms).

Mechanism of action

Cesia is a low-dose oral combination hormone drug. The contraceptive effect is achieved by means of special complementary mechanisms, one of which is the suppression of ovulation, an increase in the viscosity of cervical mucus, resulting in the cervical canal becoming impenetrable for spermatozoa.

With the correct use of tablets, the rate of unwanted pregnancy is less than 1 per 100 women taking this hormonal contraceptive during the year. In girls who took combined oral contraceptives (COCs), the menstrual cycle becomes more regular and less painful. In addition, there are clinical data on reducing the risk of endometriosis, ovarian cancer, and cervix.

Dosage and mode of application

Each 28-day Cesia pack consists three different doses of hormones:

  • 7 light yellow pills containing 0.100 mg desogestrel and 0.025 mg ethinyl estradiol;
  • 7 orange pills containing 0.125 mg desogestrel and 0.025 mg ethinyl estradiol;
  • 7 red pills containing 0.150 mg desogestrel and 0.025 mg ethinyl estradiol.

The blister also contains 7 green inert tablets with no hormones that serve purely as reminders.

To achieve a contraceptive effect, the pills should be taken orally within 28 days in order, which is indicated on the package, daily, with a small amount of water or any other drink (except alcohol-containing). Start taking tablets from the next package as soon as you finish the previous pack. During the period of taking 7 inert tablets, bleeding cancellation occurs by the type of menstruation. Normally, menstruation starts 2-3 days after taking the last active pill and lasts 5-7 days.

You’d better start taking pills on the first day of the period. Sometimes it is allowed to start taking tablets on day 2-3 of the period, but it is also necessary to use the barrier method of contraception during the first week of using the tablets from the first package.


There are no data on serious complications in the case of an overdose of Casia birth control pills. In cases of overdose, the following symptoms may occur: nausea, vomiting, spotting from the vagina. There is no antidote for ethinyl estradiol + desogestrel combination. The treatment is symptomatic.


Cesia hormonal tablets can significantly affect the work of almost all organs and systems. The medication should be taken only in the absence of contraindications to the use.

Use of medication is prohibited under the following conditions:

  • blood vessel thrombosis;
  • thromboembolism of the arteries;
  • atherosclerotic lesion;
  • pancreatitis;
  • liver tumors;
  • malignant neoplasms;
  • endocrine disorders;
  • individual hypersensitivity to the components of the drug.

Side effects

With prolonged use of the contraceptive or with individual intolerance of the drug, the following side effects of Cesia are observed:

  • breast tenderness;
  • spotting bleeding and breakthrough uterine bleeding;
  • a headache;
  • vaginal breakthrough bleeding;
  • venous hypertension;
  • early menopause;
  • a migraine;
  • change in libido;
  • dyspeptic phenomena (nausea, vomiting, diarrhea, constipation);
  • fluid retention,
  • swelling of tissues;
  • weight gain;
  • allergies.


When using Cesia medication, you can face side effects from the combination with other drugs. The list of risky combinations includes:

  • Ampicillin, Rifampicin, Chloramphenicol, Neomycin, antibiotics from the group of sulfonamides and tetracyclines, tranquilizers, Phenylbutazone;
  • Indandione, any dose of anticoagulant, coumarin derivatives, insulin, hypoglycemic drugs;
  • Maprotiline, tricyclic antidepressants, beta-blockers;
  • Dantrolene.

What if I miss a dose?

  • If you miss an active pill of Cesia (first 21 tabs from the blister), you need to take two pills the next day and then take the drug according to the previous scheme. In this case, for several days, there may be spotting;
  • If you missed an inert pill (last 7 tabs from the blister), you may just throw it away since it contains no hormones and does not provide a contraceptive effect.

If a woman has vomiting or diarrhea 3-4 hours after taking the drug, another pill should be taken since the absorption of ethinyl estradiol and desogestrel could be insufficient.

Cesia and pregnancy

Cesia is contraindicated for use during pregnancy and lactation. If pregnancy is detected during the use of the contraceptive, the therapy must be canceled.

However, clinical and epidemiological studies have not revealed any correlation between the increased risk of pathologies in children who have been exposed to hormones during intrauterine development.

Use after delivery or abortion

  • After giving birth, non-breastfeeding women can start using the drug after 21 days; breastfeeding women can start taking pills after 6 months after delivery.
  • After an abortion, it is recommended to start taking the drug immediately or on the second day after the operation.

Switching from other COCs

It is recommended to start taking the medication the day after taking the last pill of a combined oral contraceptive containing hormones, as a last resort – immediately after a break in taking tablets or a tablet that does not contain hormones.

Cesia and alcohol

Simultaneous use of alcohol and Cesia significantly reduces the normal absorption of the latter, so take the tablets no later than 3-4 hours before drinking alcohol and no earlier than 2-3 hours after it. In addition, alcohol-containing beverages contribute to side effects (especially thrombosis, nausea, migraine).

Special instructions

During pharmacological therapy with drugs that affect microsomal enzymes, and within 30 days after withdrawal, the barrier method of contraception must be used.

When using antibiotics, it is also necessary to use additional contraceptive methods.

In addition, you should stop taking Cesia pills to prevent the risk of thrombosis during scheduled operations and immediately after them.

Take contraceptive pills with caution in the following cases:

  • a violation of lipid metabolism;
  • excess of sex hormones;
  • arterial thromboembolism;
  • epilepsy;
  • a migraine;
  • autoimmune diseases;
  • renal or hepatic insufficiency;
  • anemia;
  • colitis;
  • hypertension.

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