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Solia Review

Solia is a monophasic birth control medication. The main ingredients are ethinyl estradiol and desogestrel. This drug is aimed at suppression of the ovulation as the way to prevent unwanted pregnancy.


Indications for use

Solia is a birth control used to control the pregnancies. Contraception is the main goal for applying this medication. Sometimes, it may be prescribed for regulation of the menstrual cycle or acne vulgaris treatment.

Mechanism of action

It is a monophasic oral contraceptive. The contraceptive effect is achieved due to the suppression of gonadotropin synthesis. As a result, the ovulation is inhibited. It also increases cervical mucus viscosity. As a result, the passing of the spermatozoa becomes difficult. It becomes difficult for an egg to maturate and attach to the uterine wall.

Solia has a beneficial effect on lipid metabolism: it increases the concentration of HDL in the blood plasma, without encouraging the change in the LDL content.

When taking this birth control, menstrual allocations become not so ample (with the initial menorrhagia), the menstrual cycle is normalized, a favorable effect on the skin is observed. The skin becomes purer.

Mode of application and dosage

Solia is intended for an oral administration. The overall regimen includes 28 pills. The daily recommended dose contained in one pill should be taken at one and the same time. It should be washed down with plenty of water without cutting or chewing. If you miss a pill find the unit “What if I miss a dose?” and find the answer to your question.


  • Risk factors for venous or arterial thrombosis;
  • Migraine with focal neurologic symptoms;
  • Thromboembolism: diagnosed or suggested;
  • Presence of a venous thromboembolism in the medical history;
  • Diabetes mellitus (with angiopathy);
  • Pancreatitis accompanied by severe hypertriglyceridemia;
  • Dyslipidemia;
  • Liver dysfunctions, hepatitis, incl. in the medical history;
  • Jaundice when taking COCs;
  • Cholelithiasis: diagnosed or suggested;
  • Rotor’s syndrome, Dubin-Johnson syndrome, Gilbert’s syndrome;
  • Hepatic tumors: diagnosed or suspected;
  • Itching, otosclerosis or its progression with a previous pregnancy or COCs application;
  • Vaginal hemorrhages of unknown etiology;
  • Smoking over the age of 35 (more than 15 cigarettes a day);
  • Pregnancy or suggestion of it;
  • Lactation period;
  • Hypersensitivity.

A patient should be cautious when there are conditions that increase the risk of venous or arterial thrombosis/thromboembolism. They are the age over 35 years, smoking, family history, obesity, dyslipoproteinemia, arterial hypertension, migraine, epilepsy, valve heart dysfunctions, atrial fibrillation, prolonged immobilization, extensive surgical intervention, surgical intervention on the lower extremities, severe trauma, varicose veins and superficial thrombophlebitis, changes in biochemical parameters (resistance of activated protein C, hyperhomocysteinemia, deficiency of antithrombin III, antiphospholipid antibodies, including antibodies to cardiolipin, diabetes mellitus not complicated by vascular disorders, Crohn’s disease, ulcerative colitis, sickle cell anemia, hypertriglyceridemia, acute and chronic liver disease.

Side effects

Side Effects caused by Solia that require drug withdrawal:

  • Cardiovascular system: arterial hypertension; rarely – arterial and venous thromboembolism (including myocardial infarction, stroke, deep vein thrombosis of the lower extremities, thromboembolism of the pulmonary artery); very rarely – arterial or venous thromboembolism of the hepatic, mesenteric, renal, retinal arteries and veins.
  • Sense organs: loss of hearing due to otosclerosis.
  • Other: hemolytic-uremic syndrome, porphyria; rarely – exacerbation of reactive systemic lupus erythematosus; very rarely – Sydenham’s chorea (passing after the drug withdrawal).
  • Other side effects that occur more often, but less severe. The reasonability of continuing the use of the drug is made up individually after consultation when all pros and cons are estimated.
  • Reproductive system: acyclic vaginal bleeding/spotting, amenorrhea after drug withdrawal, changes in the state of vaginal mucus, development of inflammatory vaginal processes, candidiasis, stress, pain, breast enlargement, galactorrhea.
  • Digestive system: nausea, vomiting, Crohn’s disease, ulcerative colitis, the appearance or exacerbation of jaundice and/or itching associated with cholestasis, cholelithiasis.
  • Dermatological reactions: erythema nodosum, exudative erythema, rash, chloasma.
  • Central nervous system: headache, migraine, lability of mood, depression.
  • Organ of vision: increasing the cornea sensitivity (when wearing contact lenses).
  • Metabolism system: fluid retention, change (more commonly – increase) in body weight, reduced tolerance to carbohydrates.
  • Other: allergic reactions.


Medicinal agents inducing hepatic enzymes such as hydantoin, barbiturates, primidone, carbamazepine, rifampicin, oxcarbazepine, topiramate, felbamate, griseofulvin, and drugs containing St. John’s wort, decrease the effectiveness of oral contraceptives and increase the risk of vaginal hemorrhages of unclear etiology.

Ampicillin, tetracycline provokes the reduction in the birth control pills effectiveness (the mechanism of interaction is not established).

Oral contraceptives can decrease tolerance to carbohydrates, increase the need for insulin or oral antidiabetics.

What if I miss a dose?

If you miss a dose within the first 12 hours, just take the tablet at the moment you understand what’s happened. If more than 12 pass you have to take the pill and use additional methods of contraception. If the menstruation doesn’t come you’d better examine the possibility to become pregnant.

If the dose is missed during the 3rd trimester of menstrual cycle you may throw the pill away or take another one and use additional contraception. At the end of the blister, you should be sure you are not pregnant to continue taking Solia.

Solia and pregnancy

The use of the drug during pregnancy and during breastfeeding is contraindicated. During the period of breastfeeding, it is necessary to estimate the risk to the baby and decide to withdraw or continue taking Solia. Many birth control drugs can adversely affect the embryo or fetus and even lead to the developmental defects of the unborn child. In addition, the medications taken enter the body with the breast milk and have an effect on it. Therefore, pregnant and breastfeeding women should be very cautious about the use of drugs.

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