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Reclipsen Review

Reclipsen is an oral combination birth control pill used to prevent pregnancy. The drug contains 2 female hormones: desogestrel and ethinyl estradiol.


Indications for use

  • Reclipsen is used as an oral contraceptive;
  • Also, the tablets are prescribed to treat symptoms of premenstrual syndrome and minimize pain in the mammary glands before menstruation and menstrual pain, reduce the likelihood of cancer oncology of the reproductive system.

Mechanism of action

Ethinyl estradiol and desogestrel combination oppresses pituitary secretion of gonadotropic hormones. The contraceptive effect is due to the effect on the hypothalamic-pituitary-ovarian system. Ethinyl estradiol is a synthetic analogue of the follicular hormone estradiol, which participates together with the hormone of the yellow body in the implementation of the menstrual period. The gestagenic preparation (desogestrel) inhibits the synthesis of LH and FSH by the pituitary (prevention of ripening of the follicle) and thus blocks ovulation. The contraceptive effect is also due to a decrease in the susceptibility of the endometrium to the blastocyst, as well as an increase in the viscosity of the mucus located in the cervix, which makes it relatively impenetrable for spermatozoa. The medication as a beneficial effect on lipid metabolism: increases the concentration of HDL in the plasma, without affecting the content of LDL. It also has a beneficial effect on the skin – improves its condition with acne vulgaris. With regular administration, has a therapeutic effect, normalizes the menstrual period and prevents the development of a number of gynecological diseases, including tumors.

Dosage and mode of application

Reclipsen 28-day pack contains 21 active pills (ethinylestradiol 0.03 mg, desogestrel 0.15 mg) and 7 inert pills (with no hormones).

The drug is taken orally, 1 tablet a day (starting no later than the 5th day of the period, the 1st day of the period is the 1st day of menstruation) 28 days in a row, without interruption. In the first 14 days, additional contraceptive measures should be used. If more than 5 days have passed since the beginning of menstruation, begin a pack with the next period.

Once you have taken the last pill from the blister, start taking pills from a new package.

After delivery, the drug should be taken on the first day of the first independent menstruation. After a miscarriage or artificial abortion, birth control pills must be taken immediately.


Symptoms of overdose: a severe headache, dyspepsia, cramps in the calf muscles.

Therapy is only symptomatic since there is no specific antidote.


Reclipsen is contraindicated in the following conditions:

  • pregnancy;
  • hepatitis with a previous pregnancy;
  • decompensated myocardial infarction;
  • Dubin-Johnson syndrome;
  • hypersensitivity to the acting, auxiliary components;
  • Gilbert’s syndrome;
  • angiopathy;
  • hepatic insufficiency;
  • endometriosis;
  • otosclerosis;
  • breastfeeding (reduces lactation);
  • Rotor Syndrome;
  • oncological pathologies of the liver;
  • hemangioma of the liver;
  • myocarditis;
  • a thromboembolism in the anamnesis;
  • a history of thrombosis;
  • prolonged immobilization;
  • atherosclerosis;
  • fibroadenoma of the mammary glands;
  • an increased risk of thromboembolism;
  • stroke injuries in the anamnesis;
  • IHD;
  • diabetes mellitus with angiopathy;
  • metrorrhagia;
  • retinopathy;
  • breast cancer;
  • transient violations of the cerebral circulation;
  • porphyria;
  • violations of lipid metabolism;
  • hormone-dependent tumors in gynecology;
  • severe arterial hypertension;
  • sickle cell anemia.

The drug is used with caution in smoking patients over 35 years of age.

Side effects

Reclipsen can cause the following side effects:

  • gastralgia;
  • a headache;
  • thromboembolism;
  • nausea;
  • changes in glucose tolerance;
  • hearing loss;
  • vomiting;
  • cholestatic jaundice;
  • edema;
  • dryness of the mucous eyes;
  • chloasma;
  • engorgement of mammary glands;
  • erythema nodosum;
  • breast tenderness;
  • visual impairment;
  • generalized pruritus;
  • increased blood pressure;
  • conjunctivitis;
  • “flies” before the eyes;
  • smearing excreta;
  • thrombophlebitis;
  • cholelithiasis;
  • change in vaginal secretion;
  • increase in body weight;
  • hepatocellular adenoma.

If you have any of the above adverse reactions, consult your doctor.


To prevent a decrease in contraceptive effect, it is recommended not to combine Reclipsen with the following drugs (groups of drugs):

  • rifampicin;
  • isoniazid;
  • ampicillin;
  • penicillins;
  • hydantoin;
  • topiramate;
  • griseofulvin;
  • chloramphenicol;
  • tetracycline;
  • oxcarbazepine;
  • felbamate;
  • neomycin;
  • adsorbents;
  • barbiturates;
  • carbamazepine.

Hormonal contraceptives are able to reduce the effectiveness of diazepam, anticoagulants, purine-type alkaloids, antidepressants, hypoglycemic agents, glucocorticosteroids, clofibrate.

What if I miss a dose?

If you missed an active pill (1-22 tablets):

The full contraceptive effect is maintained if the delay in taking tablets is no more than 12 hours. If more time has passed, take 2 tablets of the drug the next day at the usual time and use additional contraception during the next 14 days or until the next menstruation.

If you missed an inert pill (22-28 tablets):

Throw the missed tablet away and continue taking pills according to the usual schedule. No additional contraception is required.

Reclipsen and pregnancy

The use of Reclipsen contraceptive during pregnancy is contraindicated. If you become pregnant during taking birth control pills, stop taking them. Extensive epidemiological studies have not revealed an increased risk of birth of children with congenital defects in women taking ethinylestradiol and desogestrel prior to pregnancy or teratogenic effects with the unintentional use of hormonal contraceptives at the beginning of pregnancy.

Reclipsen can affect lactation, as ethinylestradiol and desogestrel reduce the amount and change the composition of breast milk. Therefore, the use of this drug is not recommended until a woman completely stops breastfeeding.

A small number of contraceptive steroids and/or their metabolic products may be excreted with milk.

Special instructions

The condition of a woman must be carefully monitored. If you notice the following conditions during the use of the medication, stop taking the drug and switch to another method of contraception:

  • epilepsy;
  • a migraine;
  • cholelithiasis in an anamnesis;
  • risk of developing an estrogen-dependent tumor or estrogen-dependent gynecological diseases;
  • diabetes;
  • diseases of the hemostatic system;
  • all diseases in which blood circulation disorders are most likely to occur: latent or obvious heart failure, renal insufficiency, and the presence of these
  • diseases in an anamnesis;
  • severe depression, including in the anamnesis.

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