Common brands: Estarylla, MonoNessa, Ortho-Cyclen, Ortho Tri-Cyclen, Ortho Tri-Cyclen Lo, Previfem, Sprintec, Tri-Lo-Sprintec, TriNessa, TriNessa 28, Tri-Previfem, Tri-Sprintec
Active ingredient: norgestimate and ethinyl estradiol
Manufacturer: NorthstarRx LLC Pharmaceuticals
Hormonal component: progestin and estrоgen
Release form: pills
Hormone dose: low dose
Dosage: 0.250 mg/0.035 mg
Quantity: 28 pills
Average price: $38
Mono-Linyah is a birth control drug for pregnancy prevention. It is a monophasic combined hormonal contraceptive.
Indications for use
Mechanism of action
This drug is a combined hormonal contraceptive for oral administration. The drug action is produced by means of central and peripheral mechanisms.
Mono-Linyah affects the maturation of eggs in the ovaries and ovulation by suppressing the secretion of gonadotropins.
Additionally, Mono-Linyah magnifies the viscosity of the cervical mucus, which makes it difficult for sperm to penetrate the uterine cavity and influences the endometrium epithelium, decreasing the attachment of implantation.
Mode of application and dosage
If there is no reception of any hormonal contraceptives in the previous month, Mono-Linyah is started on the 1st day of the menstrual cycle (ie, on the 1st day of menstruation). It is allowed to start taking the menstrual cycle on the 2nd-5th day, but in this case, it is recommended to use the barrier method of contraception during the first 7 days of taking the tablets from the first package.
- Thrombophlebitis or thromboembolic disorders (including thrombophlebitis of deep veins, thromboembolic disorders in history);
- Deficiency of III antithrombins;
- Atherosclerosis of cerebral vessels;
- Coronary sclerosis (myocardial infarction);
- Sickle-cell anemia;
- Diagnosed or suspected breast or uterine cancer, or other estrogen-dependent neoplasms;
- Bleeding from the genital tract of unclear etiology;
- Benign or malignant liver tumors;
- Severe hepatic dysfunction;
- Jaundice in the medical history or itching during pregnancy;
- Herpes during pregnancy in the medical history;
- Diagnosed or suspected pregnancy;
- Digestive system: nausea, vomiting, cholestatic jaundice, liver dysfunctions, accompanied by itching; rarely – gallbladder disease, hepatic adenoma.
- Central nervous system: migraine, headache, depression.
- Dermatological reactions: pigment spots on the face, hair loss.
- Organs of senses: a feeling of discomfort when wearing contact lenses.
- Reproductive system: vaginal candidiasis, erosion of the cervix, increased secretion of uterine mucus.
- Endocrine system: menstrual-like bleeding, spotting, amenorrhea, a feeling of tension шт the mammary glands, secretion from the nipples; change in body weight (increase or decrease), change in libido.
- When menstrual bleeding occurs, the reception of this birth control drug should be continued. If the bleeding does not stop, then an examination should be carried out to eliminate organic causes. Similar recommendations apply to spotting, which may appear irregularly during several cycles of receiving this birth control or for the first time after a long-lasting use of the drug.
- Other: cutaneous manifestations of allergic reactions; rarely – an increase in blood pressure, a decrease in glucose tolerance, the growth of uterine fibroids.
A contraceptive effectiveness may decrease in women who take antibiotics (ampicillin, tetracycline, rifampicin), barbiturates, antiepileptic drugs (hydantoin, carbamazepine), griseofulvin and phenylbutazone.
What if I miss a dose?
If you miss the usual time of admission, the tablet should be taken immediately. A delay from the usual intake time to 12 hours ensures proper contraceptive effect. The effectiveness of the drug is reduced when the delay in taking the tablet is more than 12 hours. If the usual time of taking the drug has been more than 12 hours or more than 1 tablet is missed, then to avoid the appearance of premature menstrual bleeding, immediately resume the drug, leaving the missed tablet in the package. However, before the end of this cycle, additional means of protection from pregnancy, such as a condom or vaginal contraceptive suppositories, should be used. In such situations, one cannot rely on the method of “safe days” or “temperature” method of contraception.
Mono-Linyah and pregnancy
Mono-Linyah is contraindicated for use in a confirmed or suggested pregnancy. The use of hormonal contraceptives at an early stage of pregnancy can cause the fetus malformations.
Small amounts of the drug may penetrate in breast milk. The drug influence on an organism of the infant is improbable. However, nursing mothers should not use hormonal contraceptives for oral administration until they stop breastfeeding. During lactation, it is recommended to use non-hormonal contraceptives.