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Tri Femynor Review

Tri Femynor is a triphasic low dose means to prevent pregnancy. This drug is prescribed to protect herself from an unwanted pregnancy.



Indications for use

Tri Femynor is prescribed to women to control conception.

Mechanism of action

Tri Femynor has performed the functions by means of mechanisms: central and peripheral.

According to the central mechanism, this birth control drug provokes a sudden decrease in the secretion of a gonadotropin-releasing factor. This decrease results in inhibition of the FSH production by the pituitary gland (due to exogenous estrogen) during the proliferative phase. This inhibition delays the growth and maturation of the follicles in the ovaries. Exanthropic progestins suppress the LH secretion by the pituitary gland. This suppression contributes to suppression of ovulation. There is a decrease in the synthesis of endogenous estrogen and progestin.

Within the peripheral mechanism, this drug levels up the cervical mucus viscosity. It makes it difficult for sperm to penetrate the uterine cavity.

The reduced peristalsis of the fallopian tubes results in untimely penetration of a fertilized egg into the uterine cavity. Under the influence of combined estrogen-progestin drugs, there are changes in the endometrium structure. It, in turn, complicates the normal fertilized egg implantation.

Mode of application and dosage

Tri Femynor is prescribed for a daily regimen including 28 pills taken without interruption. Every pill is intended for an intake approximately at the same time. It is necessary to wash the pill down with a small amount of water The correct order is specified on the package. Taking the pills from the new package is started the day after taking the last tablet from the previous package.


If you feel vomiting, nausea or you have observed vaginal bleeding you may suppose it is an overdose. In case of overdose, it is mandatory to wash stomach (within the first hour after a possible overdose) and to carry out symptomatic therapy which is prescribed by your healthcare giver.


If you are going to start taking Tri Femynor, it is important to get acquainted with its contraindications listed below:

  • currently diagnosed or prior transferred venous thrombosis inclusively of deep vein thrombosis and pulmonary thromboembolism;
  • currently diagnosed or prior transferred arterial thrombosis including acute cerebrovascular accident, myocardial infarction, retinal artery thrombosis, angina pectoris or transient ischemic attack;
  • thromboembolism
  • arterial hypertension;
  • cerebrovascular disorders;
  • coronary heart disease;
  • diabetes mellitus followed by vascular disease;
  • genetic dyslipoproteinemia;
  • hypersensitivity to any constituents of the drug;
  • migraine with aura;
  • breast and endometrium carcinoma or other estrogen-dependent neoplasms;
  • hepatic failure;
  • benign or malignant hepatic tumors;
  • hemolytic anemia;
  • sickle-cell anemia;
  • otosclerosis;
  • bleeding of unclear genesis;
  • postmenopausal period;
  • age up to 18 years;
  • puerperal period within 4 weeks;
  • pregnancy and breastfeeding.

It is necessary to be careful if you have the following medical conditions:

  • ulcerative colitis;
  • extended immobilization or major surgery;
  • risk factors for coronary heart disease, such as smoking, hyperlipidemia, hypertension, or obesity;
  • mastopathy;
  • uterine fibroids;
  • depression;
  • dysfunctions of the liver and gallbladder;
  • epilepsy;
  • tuberculosis;
  • Crohn’s disease;
  • systemic lupus erythematosus;
  • kidney disease;
  • acute abnormal liver function during a previous pregnancy or prior use of sex hormones;
  • violations of the menstrual cycle.


Side effects

  • Cardiovascular system: increased blood pressure, heart attack, a disorder of cerebral circulation, deep vein thrombosis, arterial thromboembolism, edema.
  • Hepatobiliary system: cholestatic jaundice, Budd-Chiari syndrome, intrahepatic cholestasis, cholelithiasis.
  • Gastrointestinal tract: nausea, vomiting, abdominal pain, flatulence, colitis, anorexia.
  • Genital organs: intermenstrual bleeding, spotting, amenorrhea, menstrual cycle changes, increase in uterine fibroids size, vaginal candidiasis, cervical secretion increase, cervical erosion, changes in libido, painful premenstrual syndrome, temporary infertility after the drug withdrawal.
  • Breast glands: a sensation of tension, galactorrhea, increase in size, decrease in lactation when Tri Femynor is taken immediately after birth.
  • Skin: erythema nodosum, skin rash, chloasma, exudative erythema, acne, seborrhea, alopecia, hirsutism, pigment facial spots, hypertrichosis.
  • Organs of vision: cataract, the optic nerve lesion, change in the corneal curvature, discomfort when wearing contact lenses.
  • CNS: headache, mood changes, irritability, depression, chorea, dizziness, migraine.
  • Metabolism: fluid retention, changes in body weight (decrease or increase), decreased glucose tolerance, changes in appetite.
  • Renal condition: decreased renal function, hemolytic-uremic syndrome.
  • Tumors: benign and malignant tumors of the liver, cervical and breast cancer.
  • Others: kidney disease, decreased libido.



There observed the increase in the metabolism of Tri Femynor when combining with:

  • Hypericum perforatum;
  • barbiturates;
  • carbamazepine;
  • phenytoin;
  • sulfonamides;
  • derivatives of pyrazolone;
  • rifampicin.

When taken together with some antibiotics (for example, ampicillin or tetracycline), there is an insufficient cleavage of estrogen and fatty acids by intestinal bacteria.

Some protease inhibitors and some antiretroviral drugs have affected the increase or decrease in the concentration of combined hormonal contraceptives in the plasma.

When combining ethinyl estradiol and norgestimate with hypoglycemic drugs the dose adjustment of the latter may be required.

What if I miss a dose?

Thes recommendations belong to the missing of active pills only. If you forget to take placebo pill it can be just thrown away.

If a woman misses the pill containing hormones for less than 24 hours, the contraceptive reliability is not changed. A woman should take the missed pill in at the moment she understands the missing. Then, the regimen should be continued.

If a woman delays taking the pill containing hormones for more than 24 hours, the contraceptive reliability may be changed considerably. Remember the more pills you have missed within a monthly course the greater the risk to become pregnant.

Each blister contains the rules on how to act in the case of missing tablets. Tri Femynor is a triphasic drug that’s why the closer the missed pill to the end of the course the higher the risk of conceiving a child.

Tri Femynor and pregnancy

Tri Femynor has categorized in the FDA as X. This medication is contraindicated for an application by pregnant women.

The conducted epidemiological trials have not specified a high risk of birth dysfunctions in children if their mothers applied oral birth control before pregnancy. Most modern studies have not revealed any heart abnormalities and shortening of the extremities in children born by mothers taking hormonal birth control on the early stages of pregnancy.

Tri Femynor can influence breastfeeding. It reduces the quantity of breast milk changing its composition. Finally, women should consult a doctor when they are allowed to renew the course of contraceptives.


I was on this contraceptive pill for almost 5 years, I started to cry almost every day. Hormones made me extremely emotional. I have to get off the pill next month. Yes, the pill cleared up my acne, but mood swings were just not worth it to me.
- Mary Merlin

I’ve been on Tri Femynor for about 8 months now and for 3 of those months I have not stopped bleeding. Think twice before taking.
- Delana Williams

It made my period less abundant and reduced the symptoms of PMS. However, it made me more emotional.
- Laura Santos

I am a healthy young woman and began taking the contraceptive 6 months ago. I am experiencing terrible and frequent mood swings and crying VERY OFTEN. I am going to stop taking this birth control.
- Antoinette Heaton

Tri Femynor gave me headaches and acne. May be it will work for you.
- Suzanne Izaguirre

My GYN changed me to this pill about a year ago. The pill does its job, so I am happy with that part. BUT it caused dark sun spots on the face)!
- Lydia Lebron

I’ve been on this pill for 11 months now and the first week I had nausea and headaches. Not sure what caused it, possibly it was this contraceptive.
- Martha Goodwin

Worked fine as a birth control but gave me the worst acne in my life thus far (& I went on it to treat mild acne /: ). Took it for 90 days and didn’t want to risk getting acne at the same rate I have been getting it. Triphasic might not be for me. Switching to Givani this month
- Marie

This pill works wonderfully, I've been on it for about 7 months now. Prior, I was on Lo Loestrin which I also loved but I switched insurances and it didn't cover it anymore. Tri Femynor gives the benefit of a contraceptive PLUS amazing skin. Prior to this birth control, my skin care regimen included 3 products (2 which were actually prescriptions). After 5 months of being on this pill, my regimen now is just simply splashing water on my face; that's how well this pill controls acne. I give it four stars only because the periods are consistently very heavy on this pill, especially on day two when on the placebo week. I need to use a pad plus a tampon and I still can leak through if I don't change regularly (especially on my sheets). The period is about 4 days and the heaviness is only on day two so it isn't TOO inconvenient. However, on Lo Loestrin I could get away with just a panty-liner the whole day and it was only a 2 day period so I really miss that feature. But because of the amazing skin benefits, I don't see myself changing pills any time soon.
- Tess

No Complaints except weight gain, my face looks clear though!!
- Madi

I’ve been using Tri Femynor for about 9 months. The only complaints I have are nausea and weight gain. I’ve gained over 8 pounds with this contraceptive l and now I want to switch to another pill. With this pill, my skin looks amazing - no acne any longer but I’m feeling really depressed with the weight gain. Can anyone recommend a good option?
- Lucy

I'd recommend Mononessa. I was using it for about 11 months and it cleared my face completely! I didn’t have headaches or depression. My periods became regular. I haven’t gained any weight. My girlfriend is currently on Tri Femynor and she has no complaints either.
- Alexandra

I've been on Tri Femynor for almost a year and cannot say anything bad about this pill. I’ve tried other forms of contraception and this one the best for me.
- Alicia

I’ve only been on this pill for 2 months and I’ve noticed very emotional mood swings. Sometimes I can be extremely irritable and I can cry every day for no reason! After the current pack is finished I will consult a doctor about switching to another pill.
- Jane

I have been using this birth control for 3 years. Before I switched to Tri Femynor, I tried Sprintec, Alesse, Trinessa, etc. This pill gave me headaches, stomach pains, nausea, and dizziness! And now I'm having abdominal pain for no reason. I hate this medication and cannot wait to switch to another pill as soon as possible!!!
- Katie

I started this medication because I had irregular and heavy periods. My gyno prescribed Femynor. My periods are regular now and I feel no pain at all. The only side effect I noticed was nausea but after about a month it disappeared.
- Sadie

I am 34 years old. My doctor prescribed this pill for heavy periods. Since then I have had no issues with heavy bleeding and have been taking Tri Femynor now for 10 months. The only side effects I’ve had are mood swings and weight gain.
- Christine

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