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Deblitane Review

Deblitane is mini-pills birth control drug. It is prescribed for pregnancy prevention by increasing the viscosity of cervical secretion.


Indications for use

Prevention of pregnancy.

Mechanism of action

Deblitane is a steroid progestin that affects on the female reproductive (fertile) function. It suppresses ovulation, prevents the already fertilized egg from attaching to the uterine wall, arresting the onset of pregnancy. The contraceptive effect is approximately 97%.

Mode of application and dosage

The medicine should be taken from the 1st day of the menstrual cycle – 1 tablet of Deblitane at the same time, either after breakfast or at bedtime. After applying the tablets from the first package, it is necessary to start the next package, regardless of whether there is currently menstruation or not. There is a possible delay in menstruation when taking this birth control, but not more than 45 days. In such cases, it is necessary to consult a gynecologist to find out the possibility of pregnancy.

Vomiting or diarrhea can lead to a withdrawal of the taken medicine from the body, therefore, in those cases when these symptoms occur within 1 day, the pill must be taken repeatedly. With longer preservation of these symptoms, it is temporary to resort to other methods of preventing pregnancy.


  • Thrombophlebitis (inflammation of the veins);
  • Swelling of the mammary gland or genital organs;
  • Prior transferred stroke (acute violation of cerebral circulation);
  • Cardiac ischemia;
  • Angina pectoris;
  • Epilepsy;
  • Diabetes;
  • Arterial hypertension;
  • Cholecystitis (gallbladder inflammation);
  • Mental disorders;
  • Uterine bleeding;
  • Suspicion of pregnancy.

Side effects

Deblitane provokes the following side effects:

  • hypercoagulability;
  • thromboembolic conditions (vascular blockade);
  • increased risk of cerebrovascular accident;
  • tenderness in the mammary glands;
  • nausea;
  • vomiting;
  • changes in weight;
  • pigmentation of the face skin and swelling of the ankle joint.
  • Rare side effects are:
  • uterine bleeding;
  • violation of the menstrual cycle;
  • jaundice;
  • depressive state.


Interactions between mini-pills and other medicinal products can cause acyclic bleeding and (or) a decrease in the contraception effectiveness.

Hepatic metabolism

Possible interactions with drugs that induce hepatic enzymes can lead to increased clearance of sex hormones (eg, phenytoin, barbiturates, primidone, carbamazepine and rifampicin, bosentan and drugs used in the treatment of HIV infection (ritonavir, nevirapine), and probably also oxcarbazepine, topiramate, felbamate, griseofulvin, and medicines containing St. John’s wort (Hypericum perforatum)). Maximal enzymatic induction usually occurs within about 10 days, but can then persist for at least 4 weeks after discontinuing drug therapy.

Influence on intestinal-hepatic circulation

A decrease in the effectiveness of contraception is also described when used simultaneously with antibiotics such as penicillins and tetracyclines. The mechanism of this phenomenon is unknown.

What if I miss a dose?

The contraceptive effect of the drug does not decrease if the admission of the tablet does not exceed 12 hours. Deblitane should be taken as soon as possible and in the future tablets should be taken at the usual time.

If the delay in taking the tablet exceeds 12 hours, the contraceptive reliability of the drug may be reduced. In this case, following the main rules:

  • the birth control pills should be taken for more than 7 days in raw without any interruptions;
  • to adequately suppress the hypothalamic-pituitary-ovarian system, the tablets should be taken within 7 days.

Deblitane and pregnancy

Deblitane is contraindicated during pregnancy and breastfeeding.

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