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Kelnor 1/35 Review


Kelnor 1/35 is a monophasic contraceptive medication with a low-dose hormone. The main components are ethynodiol diacetate and ethinyl estradiol. The drug is directed to suppress an ovulation and prevents the egg maturation.

Contents:

Indications for use

This drug is prescribed for contraceptive means. The unwanted pregnancy is prevented by means of this birth control preparation.

Mechanism of action

Kelnor 1/35 is a combined monophasic oral contraceptive. The mechanism of action is associated with the suppression of the hypothalamic-pituitary system function, the suppression of the gonadotropic hormones’ production, which leads to the ovulation suppression. In addition, the viscosity of the cervical mucus increases, the transport function of the fallopian tubes decreases, the implantation ability of the endometrium changes.

Mode of application and dosage

Take 1 pill per day for 28 days. Then the menstruation will come, during which the birth control is not accepted. You can take pills on various schemes: on the charts “Sunday” and “5th day.” These are different methods of starting the reception, the different days of reception are determined according to the cycle. The pill application should be on the first day of menstruation and continue for 21 days. Then, as usual, inactive 7 pills should be taken.

In order not to reduce the effectiveness of the oral contraceptive, 2 or more drugs should not be taken. Their interaction can weaken or strengthen the protective drug functions, can cause overdose and poisoning. If there are any side effects, you should stop taking the medication and consult a doctor.

Contraindications

  • Pregnancy and lactation;
  • Mammary glands and reproductive system tumors;
  • Spotting from the genital tract of unclear etiology;
  • Thrombophlebitis;
  • Thromboembolic disease;
  • Hepatic disorders and other disorders related to its function;
  • Kidney dysfunction;
  • Diabetes mellitus of severe form;
  • Severe fat metabolism dysfunctions;
  • Sickle cell anemia.

The drug is not recommended to prescribe for smoking women over 35 years of age and women over 40 years of age.

Side effects

  • Intermenstrual bloody allocations;
  • Mammary glands tenderness;
  • Nausea;
  • Vomiting;
  • Increased blood pressure or hypertension;
  • Headache, depression;
  • Change in body weight;
  • Skin rash.

Interactions

Possible interactions: drugs that induce microsomal enzymes: such a combination can increase clearance of sex hormones, which in turn can lead to breakthrough uterine bleeding and/or a decrease in the contraceptive effect.

Women who admit treatment with these drugs are recommended to apply a barrier method of contraception or choose a different non-hormonal method of contraception.

Means that increase Kelnor 1/35 clearance (weakening the effectiveness by induction of enzymes): phenytoin, barbiturates, primidone, carbamazepine, rifampicin and possibly also oxcarbazepine, topiramate, felbamate, griseofulvin, and preparations containing St. John’s Wort.

Means with different effects on Kelnor 1/3 clearance: many HIV protease or hepatitis C virus inhibitors reverse transcriptase inhibitors can both magnify and reduce the concentration of estrogens or progestins in the plasma. In some cases, such an effect may be clinically significant.

Means that reduce the clearance of combined oral contraceptives (enzyme inhibitors): strong and moderate inhibitors of CYP3A4, such as antifungal agents of the azole group (eg itraconazole, voriconazole, fluconazole), verapamil, macrolide antibiotics (eg clarithromycin, erythromycin), diltiazem and grapefruit juice can increase plasma concentrations of estrogen or progestin or both.

What if I miss a dose?

If a dose is missed, see the instructions for use or contact your doctor for further instructions. If you use this drug to prevent pregnancy, you may need to use another form of contraceptives to prevent pregnancy for some time.

Kelnor 1/35 and pregnancy

Kelnor 1/35 is contraindicated during pregnancy and breastfeeding. The drug category according to the US FDA is X. If the drug is taken it is better to postpone breastfeeding within 24 hours.

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