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Tydemy Review

Tydemy is an oral contraceptive which contains ethinyl estradiol, drospirenone, and levomefolate calcium. The drug is used to prevent pregnancy.


Indications for use

  • Contraception.

Mechanism of action

The active substances inhibit ovulation and produce a qualitative effect on the endometrium of the uterus. Drospirenone has antiandrogenic and soft antimineralocorticoid properties.

Weak antimineralocorticoid properties have a weak antimineralocorticoid effect.

Dosage and mode of application

Take 1 tablet a day, at the same time of the day, for 28 days in a row. Follow the order indicated on the blister.

Start each next Tydemy pack the day after the previous one is finished.

Menstruation should begin on the 2nd-3rd day after the start of taking inert tablets and may not stop before the start of the next package.

If you had an abortion in the first trimester, the drug is taken on the day of the surgery.

If an abortion was made in the second trimester of pregnancy, or a woman wants to start taking an oral contraceptive after delivery, the reception starts on the 21-28th day.

A contraceptive effect is not guaranteed in the first week of admission. Therefore, it’s recommended to use barrier methods of contraception.

Side effects

Tydemy tablets can cause the following side effects:

  • nausea;
  • pain in the mammary glands;
  • irregular uterine bleeding;
  • bleeding from the genital tract of unspecified genesis;
  • arterial and venous thromboembolism;
  • migraine;
  • mood swings;
  • depressed mood.


Tydemy birth control pills are contraindicated in the following conditions (current and in the anamnesis):

  • thrombosis (venous and arterial) and thromboembolism, cerebrovascular disorders;
  • conditions preceding thrombosis (transient ischemic attacks, angina pectoris);
  • acquired or hereditary predisposition to venous or arterial thrombosis;
  • venous or arterial thrombosis;
  • migraine with focal neurologic symptoms;
  • pancreatitis with severe hypertriglyceridemia;
  • diabetes mellitus with vascular complications;
  • hepatic failure and severe liver disease;
  • renal failure;
  • liver tumors;
  • hormone-dependent malignant neoplasms;
  • bleeding from the vagina of unknown origin.
  • pregnancy and breastfeeding period;
  • increased sensitivity or intolerance to any of the components of the drug (ethinyl estradiol, drospirenone, levomefolate calcium).

With caution: smoking, obesity, dyslipoproteinemia, controlled arterial hypertension, migraine without focal neurologic symptoms, uncomplicated heart valve defects, hereditary predisposition to thrombosis, diabetes mellitus without vascular complications, systemic lupus erythematosus, hemolytic uremic syndrome, Crohn’s disease, ulcerative colitis, sickle cell anemia, phlebitis of superficial veins, hereditary angioedema, hypertriglyceridemia, diseases that first appeared or worsened during pregnancy or on the background of previous use of sex hormones, postpartum period.


Do not combine Tydemy tablets with antibiotics (penicillins and tetracycline) since they can reduce intestinal hepatic recycling of estrogens, thereby reducing the concentration of ethinylestradiol.

Pregnancy and breastfeeding

This drug is contraindicated in pregnancy and lactation.

What if I miss a pill?

If you missed an active tablet, take it as soon as you remember it. The next tablet is taken the next day at the usual time. If the delay is less than 24 hours, the contraceptive properties of the drug are not reduced. If the break is more than 24 hours, the contraceptive effect can be reduced. If you missed an inert tablet, you may not worry and just throw it away.


It’s necessary to carefully weigh the potential risk and expected benefits of Tydemy in each individual case.

The drug is not used after menopause.

Inform all health care providers that you are taking birth control pills. You may need to stop taking this medication before performing certain types of surgery in accordance with your doctor’s instructions.

This contraceptive may increase the risk of blood clots, stroke or myocardial infarction.

This drug contains drospirenone. The risk of blood clots when using drospirenone-containing medications may be higher than with other contraceptive pills.

Prolonged immobility can increase the risk of blood clots.

If you have diabetes, consult a doctor. This drug can increase blood sugar.

Check the blood sugar level as directed by your doctor.

If you are using a salt substitute containing potassium, a potassium-sparing diuretic or a potassium supplement, consult your doctor.

The use of drugs of this kind was accompanied by high blood pressure. Monitor your blood pressure as directed by your doctor.

Carry out blood tests as directed by your doctor.

Regularly undergo a breast and gynecological examination. The attending physician will tell you how often you need to do this. It is also necessary to perform self-examination of the mammary glands in accordance with the instructions of the attending physician.

This drug may affect the results of some laboratory tests. Notify all health care workers and the laboratory personnel that you are taking this medication.

The medication can cause the formation of pigment spots on the face. Avoid exposure to sunlight, do not go to the solarium. Use sunscreen, wear sun protective clothing and sunglasses.

Some medicines and herbal remedies can reduce the effectiveness of this drug. Be sure to inform your doctor about all medications you are taking.

Tydemy does not prevent the spread of diseases that are transmitted through the blood or sexually.

Do not use this contraceptive if you have not yet had your first menstrual period.

Immediately contact your doctor if you notice any signs of pregnancy.

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