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Vestura Review

Vestura is a combination oral contraceptive containing 2 female hormones known as ethinyl estradiol and drospirenone. The drug is used to prevent pregnancy.


Indications for use

  • Contraception;
  • Contraception and treatment of a moderate form of acne vulgaris;
  • Contraception and treatment of a severe premenstrual syndrome.

Mechanism of action

The contraceptive effect of Vestura is based on suppression of ovulation and a change in the properties of the secretion of the cervix, resulting in it becoming impermeable to spermatozoa.

Dosage and mode of application

To achieve the most effective results of taking Vestura tablets, you must strictly follow the doctor’s prescriptions. As a rule, one tablet is taken once a day with a full glass of water. It is recommended to take tablets at the same time each day to achieve the most optimal reception results.

Side effects

Like any other medication, Vestura drug may cause side effects.

  • breakthrough bleeding or spotting discharge from the vagina between menstruation;
  • complete suspension of the menstrual period;
  • menstrual period disorders;
  • headache, vaginal infections,
  • high blood pressure;
  • migraine.

If these symptoms are persistent, become more severe or cause anxiety, you should consult your doctor.


Vestura tablets are contraindicated for use in the following conditions (including in the anamnesis):

  • thromboses (deep vein thrombosis, pulmonary embolism, myocardial infarction, cerebrovascular disorders);
  • conditions preceding thrombosis (transient disorders of cerebral circulation, angina pectoris);
  • diabetes mellitus with vascular complications;
  • severe or multiple risk factors for venous or arterial thrombosis;
  • severe forms of liver disease (as long as the parameters of liver samples are not normalized);
  • benign or malignant liver tumors;
  • identified hormone-dependent malignant diseases of genital organs or mammary glands;
  • severe or acute renal failure;
  • vaginal bleeding of unknown origin;
  • pregnancy;
  • lactation (breastfeeding);
  • hypersensitivity to the components of the drug (ethinyl estradiol and drospirenone).


Anticonvulsants (primidone, carbamazepine, hydantoin, barbiturates), anti-tuberculosis drugs (rifampicin), ampicillin, tetracyclines, griseofulvin may reduce the contraceptive efficacy of the drug.

ACE inhibitors, angiotensin II receptor antagonists, potassium-sparing diuretics, aldosterone antagonists, indomethacin can cause hyperkalemia when taken with drospirenone / ethinyl estradiol.

Tobacco, grapefruit juice, caffeine and alcohol may interact with Vestura.

It is necessary to discuss the use of these substances with the doctor in order to prevent unwanted complications.

Pregnancy and breastfeeding

Vestura for birth control is contraindicated in pregnancy.

Taking combined contraceptives can reduce the amount of breast milk and change its composition. Therefore, it is not recommended to prescribe this drug during breastfeeding.

What if I miss a pill?

Missing inactive tablets can be ignored.

If the delay in taking an active tablet is less than 12 hours, the contraceptive effect is not reduced. Take the missed pill as soon as possible, the next pills is taken at your usual time.

If the delay in taking an active tablet is more than 12 hours, the contraceptive effect can be reduced. The missed tablet should be taken as soon as possible (even if it means taking 2 tablets at the same time). The next tablet is taken at the usual time. In addition, you need to use the barrier method of contraception for the next 7 days.


Before using the drug, you need to conduct a general medical examination (including mammary glands) and cytological examination of cervical mucus, exclude pregnancy, violations from the coagulation system of the blood. With prolonged hormonal contraception, preventive check-ups should be performed every 6 months.

Take Vestura tablets with caution: diabetes mellitus, obesity, high blood pressure, valvular heart disease, severe cardiac rhythm disorder, surface vein phlebitis, varicose veins, thrombosis, myocardial infarction or family history, migraine, epilepsy, hyperkalemia, hypercholesterolemia or hypertriglyceridemia in anamnesis, breast cancer in a family history, liver or gall bladder disease, Crohn’s disease, systemic lupus erythematosus, sickle-cell anemia, hemolytic uremic syndrome.

The risk of developing venous thrombosis increases with age, obesity, a history of thrombosis (including family history), smoking, prolonged immobilization.

When using Vestura contraceptive, you should stop smoking, especially if you are over 35 years.

If you have symptoms of venous or arterial thrombosis: sudden coughing, sudden severe chest pain, any unusual, severe, prolonged headache, increased frequency and severity of migraine, partial or complete loss of vision, diplopia, slurred speech or aphasia, sudden changes in hearing, smell, taste, dizziness or fainting, weakness or very significant loss of sensitivity, unilateral leg pain and / or swelling, motor abnormalities, symptom-complex “acute” abdomen.

The drug may cause occasional bleeding (spotting or breakthrough bleeding), especially during the first months of use.

If irregular bleeding recurs or develops after previous regular periods, you need to exclude malignant neoplasms or pregnancy.

In some cases, during a break in taking active pills, bleeding may not occur. If the drug was taken according to recommendations, it is unlikely that the woman is pregnant, but if you missed active tablets or do not have menstrual bleeding in a row, pregnancy should be excluded before continuing contraception.

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