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Ovrette Review

Ovrette (norgestrel) is a progestin-only oral contraceptive. indicated for use by women to prevent pregnancy.


Indications for use

  • Hormonal contraception;
  • Hormone replacement therapy (as part of combination therapy).

Mechanism of action

Gestagen, contraceptive. It affects the gonadotropic function of the pituitary gland, which leads to a slight decrease in the peak of FSH and LH. It causes changes in the endometrium, which lead to disruption of the egg implantation process. It helps increase the viscosity of cervical mucus, which impedes the progress of sperm.

Dosage and mode of application

Orally. The dosing regimen is individual. The dose, frequency and duration of treatment with Ovrette are determined according to the scheme depending on the indications and the clinical situation.

Side effects

  • Reproductive system: acyclic intermenstrual bleeding, shorter cycles (less than 25 days) or oligomenorrhea (more than 45 days), engorgement of the mammary glands, decreased libido;
  • Endocrine system: a decrease in glucose tolerance, an increase in body weight, fluid retention in the body;
  • Dermatological reactions: pigmentation, acne;
  • Other: arterial hypertension, nausea, headaches.


  • Irregular menstrual cycle;
  • Acyclic uterine bleeding of unknown origin;
  • Malignant neoplasms of the mammary glands and reproductive system;
  • Heavy menstruation;
  • Severe diabetes mellitus;
  • Arterial hypertension;
  • Epilepsy;
  • History of ectopic pregnancy.


Ovrette reduces the intensity of the drugs that stimulate the smooth muscles of the uterus, anabolic steroids, gonadotropin-releasing hormone of the anterior pituitary.

It also reduces the lactogenic effect of oxytocin and enhances the action of diuretics, antihypertensive drugs, immunosuppressive drugs. Simultaneous administration of Ovrette with barbiturates weakens progesterone effects.

Pregnancy and breastfeeding

Do not use these pills during pregnancy. It is recommended that you terminate the pregnancy that occurred while taking Ovrette. It is possible to use norgestrel pills during lactation but only 6-8 months after delivery.

What if I miss a pill?

Missing pills increases the risk of pregnancy. If you miss one pill, take it as soon as you remember and also take the next pill at the regular time. If you miss two tablets, take one of the missed pills as soon as you remember, as well as take your regular pill for that day at the proper time. Furthermore, use a method of non-hormonal contraception in addition to taking birth control pills until 14 tablets have been taken. If you missed more than 2 pills, the drug should be discontinued immediately and a method of non-hormonal contraception should be substituted until the start of the next period or an appropriate diagnostic procedure should performed to exclude pregnancy.


Consult your doctor prior to using this contraceptive.

Cigarette smoking increases the risk of serious cardiovascular side effects. Do not smoke when taking Ovrette.

If you have acyclic spotting or oligomenorrhea, a thorough examination should be performed to exclude pregnancy (including ectopic) and organic pathology.

If you have overdosed and have serious symptoms such as passing out or trouble breathing, call 911 or poison control center right away.

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